Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.50 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.50 |
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.50 |
| ▸ | NEK10 | Q6ZWH5 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2410295 | 0.86 | DHODH (0.63) | DHODHPDE10ALMNATSHRHTT | |
| SCHEMBL13971502 | 0.79 | DHODH (0.77) | DHODHPDE10ALMNATSHRCYP2D6 | |
| SCHEMBL14583114 | 0.78 | PDE10A (0.77) | DHODHPDE10ALMNATSHRCYP2D6 | |
| SCHEMBL8572508 | 0.77 | LCK (0.54) | DHODHPDE10ATSHRLCKMAP2K3 | |
| Hydrochloric Acid SCHEMBL6969111 | 0.76 | PDE10A (0.75) | DHODHPDE10ALMNATSHRCYP2D6 | |
| SCHEMBL61597 | 0.76 | HSD17B10 (0.52) | DHODHPDE10ALMNATSHRLCK | |
| SCHEMBL30148539 | 0.76 | HSD17B10 (0.52) | DHODHPDE10ALMNATSHRLCK | |
| SCHEMBL2404536 | 0.74 | DHODH (0.52) | DHODHPDE10ALMNATSHRCYP2D6 | |
| SCHEMBL8271391 | 0.74 | TACR3 (0.65) | DHODHPDE10ALMNATSHR | |
| SCHEMBL27921343 | 0.72 | GAA (0.53) | LMNAMEN1KMT2AGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080090863-A1 | Pyridine Derivatives and Their Use as Medicaments for Treating Diseases Related to Mch Receptor | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090863-A1 | Pyridine Derivatives and Their Use as Medicaments for Treating Diseases Related to Mch Receptor | MCHR1, GPR119, MCHR2 | DHODH 3216/4885PDE10A 1210/4885LMNA 3000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.