Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029831 | 0.81 | CYP2C19 (0.33) | CYP2C19 | |
| SCHEMBL11294682 | 0.81 | CYP2C19 (0.33) | CYP2C19 | |
| SCHEMBL6238266 | 0.73 | CYP2C19 (0.36) | CYP2C19 | |
| SCHEMBL2960180 | 0.71 | CYP2C19 (0.35) | CYP2C19 | |
| SCHEMBL9797811 | 0.69 | CYP2C19 (0.33) | CYP2C19 | |
| SCHEMBL17938191 | 0.69 | CYP2C19 (0.33) | CYP2C19 | |
| SCHEMBL2152288 | 0.67 | CYP2C19 (0.32) | CYP2C19 | |
| SCHEMBL8721766 | 0.67 | CYP2C19 (0.32) | CYP2C19 | |
| SCHEMBL4446921 | 0.67 | CYP2C19 (0.38) | CYP2C19 | |
| SCHEMBL9346865 | 0.67 | CYP2C19 (0.32) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642798-B2 | Silacycle compounds and methods of use thereof | THE TRUSTEE OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-02-04 | — | — | US | disclosed |
| US-8642798-B2 | Silacycle compounds and methods of use thereof | THE TRUSTEE OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-02-04 | — | — | US | disclosed |
| US-20080167468-A1 | using the diastereomeric mixture of Silacycle Compounds for stereoselective synthesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-07-10 | — | — | US | disclosed |
| US-20080167468-A1 | using the diastereomeric mixture of Silacycle Compounds for stereoselective synthesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167468-A1 | using the diastereomeric mixture of Silacycle Compounds for stereoselective synthesis | LSS, CYP51A1, DHPS | CYP2C19 434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.