Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4929748 | 1.00 | NPSR1 (0.41) | NPSR1ALOX15HCAR2MAPT | |
| SCHEMBL5325153 | 1.00 | NPSR1 (0.41) | NPSR1ALOX15HCAR2MAPT | |
| SCHEMBL5279367 | 1.00 | NPSR1 (0.41) | NPSR1ALOX15HCAR2MAPT | |
| SCHEMBL4933499 | 1.00 | NPSR1 (0.41) | NPSR1ALOX15HCAR2MAPT | |
| SCHEMBL4929742 | 1.00 | NPSR1 (0.41) | NPSR1ALOX15HCAR2MAPT | |
| SCHEMBL4933494 | 1.00 | NPSR1 (0.41) | NPSR1ALOX15HCAR2MAPT | |
| SCHEMBL5330345 | 1.00 | NPSR1 (0.41) | NPSR1ALOX15HCAR2MAPT | |
| SCHEMBL5325150 | 1.00 | NPSR1 (0.41) | NPSR1ALOX15HCAR2MAPT | |
| SCHEMBL5325160 | 1.00 | NPSR1 (0.41) | NPSR1ALOX15HCAR2MAPT | |
| SCHEMBL4933491 | 1.00 | NPSR1 (0.41) | NPSR1ALOX15HCAR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194841-A1 | Preparation of Optically Pure Beta-Amino Acids Having Affinity for the Alpha-Delta Protein | PFIZER INC. | 2008-08-14 | — | — | US | disclosed |
| EP-1863780-A1 | PREPARATION OF OPTICALLY PURE BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | Pharmacia & Upjohn Company LLC (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006100568-A1 | PREPARATION OF OPTICALLY PURE BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194841-A1 | Preparation of Optically Pure Beta-Amino Acids Having Affinity for the Alpha-Delta Protein | OPRD1, CHRND, CHRNE | NPSR1 512/4885ALOX15 699/4885HCAR2 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.