Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | FASN | P49327 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 4/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4929983 | 1.00 | TSHR (0.71) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL887672 | 0.97 | TSHR (0.68) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL3678163 | 0.97 | TSHR (0.68) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL1983165 | 0.97 | TSHR (0.68) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL23040319 | 0.97 | TSHR (0.68) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL23040318 | 0.97 | TSHR (0.68) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL23040320 | 0.97 | TSHR (0.68) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL23040317 | 0.97 | TSHR (0.68) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL1983164 | 0.97 | TSHR (0.68) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL8777247 | 0.97 | TSHR (0.68) | TSHRALDH1A1FASNFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020160027-A1 | Conjugate, its preparation and use | MERCK PATENT GMBH (DE) | 2002-10-31 | — | — | US | claimed |
| US-3940340-A | Peracylated polyamines compatible with optical brighteners as activators for inorganic peroxo compounds | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-24 | — | — | US | claimed |
| WO-2014093723-A2 | GROUP-ASSISTANT-PURIFICATION (GAP) SYNTHESIS OF VELCADE, DIMERIC ANALOGS, AND AMINO COMPOUNDS | NANJING UNIVERSITY (CN) | 2014-06-19 | — | — | WO | disclosed |
| US-20080025940-A1 | Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof | L'OREAL (FR) | 2008-01-31 | — | — | US | disclosed |
| EP-0967200-A1 | 4,4-Diarylbutadienes as water soluble, photostable UV-filters for cosmetic and pharmaceutical preparations | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-29 | — | — | EP | disclosed |
| US-5491152-A | Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| US-4188274-A | DECARBOXYLATION | STANDARD OIL COMPANY (INDIANA) (US) | 1980-02-12 | — | — | US | disclosed |
| US-4174447-A | SILVER SALTS OF CARBOXY ACIDS | STANDARD OIL COMPANY (INDIANA) (US) | 1979-11-13 | — | — | US | disclosed |
| US-4001130-A | DETERGENTS, SUBSTITUTED BUTADIENES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |
| US-3972877-A | Butadiene derivatives, process for their preparation and their use as optical brighteners | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020160027-A1 | Conjugate, its preparation and use | TYR, MPO, DDT | TSHR 3767/4885ALDH1A1 71/4885FASN 1539/4885 |
| US-20080025940-A1 | Administration of 3-sulfanylpropanamide compounds for stimulating hair and eyelash growth and/or for stopping the loss and/or limiting the depigmentation thereof | KRT18, TYR, MC1R | TSHR 959/4885ALDH1A1 1607/4885FASN 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.