SCHEMBL4930841

SCHEMBL4930841

C=CCN(CC=C)N(CC=C)CCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.40
ALDH1A1 P00352 1/20 0.40
ABCC4 O15439 1/20 0.40
TSHR P16473 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
LMNA P02545 3/20 0.35
EGLN1 Q9GZT9 3/20 0.35
ALKBH5 Q6P6C2 1/20 0.35
SUCNR1 Q9BXA5 1/20 0.35
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
BLM P54132 1/20 0.34
SLC6A3 Q01959 1/20 0.34
CYP2D6 P10635 1/20 0.34
NFKB1 P19838 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2550180 0.79 KDM4E (0.43) MAPTALDH1A1ABCC4TSHRSMN1; SMN2
SCHEMBL45568 0.79 ALDH1A1 (0.41) MAPTALDH1A1ABCC4TSHRSMN1; SMN2
SCHEMBL10525527 0.77 MAPT (0.40) MAPTALDH1A1ABCC4TSHRSMN1; SMN2
SCHEMBL3210952 0.77 KDM5A (0.40) MAPTALDH1A1ABCC4TSHRSMN1; SMN2
SCHEMBL3207997 0.76 LSS (0.39) MAPTALDH1A1ABCC4EGLN1MEN1
Hydrochloric Acid SCHEMBL27738298 0.74 MEN1 (0.42) MAPTALDH1A1ABCC4EGLN1MEN1
SCHEMBL9519262 0.72 ALDH1A1 (0.45) MAPTALDH1A1ABCC4TSHRSMN1; SMN2
SCHEMBL8090929 0.71 ABCC4 (0.48) MAPTALDH1A1ABCC4TSHRSMN1; SMN2
SCHEMBL3200640 0.71 ABCC4 (0.39) MAPTALDH1A1ABCC4TSHRSMN1; SMN2
SCHEMBL3199671 0.71 FFAR3 (0.39) MAPTALDH1A1ABCC4TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080308492-A1 Filter Medium for Technical Applications, and Method for the Production Thereof MAHLE INTERNATIONAL GMBH (DE) 2008-12-18 US claimed
US-11614640-B2 Spectacle lens and method, in particular 3D printing method, for the production thereof CARL ZEISS VISION INTERNATIONAL GMBH (DE) 2023-03-28 US disclosed
US-10670884-B2 Spectacle lens and method for producing same CARL ZEISS VISION INTERNATIONAL GMBH (DE) 2020-06-02 US disclosed
US-20190250430-A1 SPECTACLE LENS AND METHOD, IN PARTICULAR 3D PRINTING METHOD, FOR THE PRODUCTION THEREOF CARL ZEISS VISION INTERNATIONAL GMBH (DE) 2019-08-15 US disclosed
US-20190243161-A1 SPECTACLE LENS AND METHOD FOR PRODUCING SAME CARL ZEISS VISION INTERNATIONAL GMBH (DE) 2019-08-08 US disclosed
US-20080308492-A1 Filter Medium for Technical Applications, and Method for the Production Thereof MAHLE INTERNATIONAL GMBH (DE) 2008-12-18 US disclosed