Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 16/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 16/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5421491 | 0.93 | HTT (0.52) | ESR1ESR2HTTLTA4HMET | |
| SCHEMBL8473947 | 0.88 | ESR1 (0.58) | ESR1ESR2LTA4H | |
| SCHEMBL1360621 | 0.88 | HTT (0.53) | ESR1ESR2HTTLTA4H | |
| SCHEMBL1359127 | 0.86 | ESR1 (0.56) | ESR1ESR2 | |
| SCHEMBL1359724 | 0.86 | ESR1 (0.56) | ESR1ESR2 | |
| SCHEMBL1359175 | 0.86 | ESR1 (0.55) | ESR1ESR2 | |
| SCHEMBL1360104 | 0.86 | ESR1 (0.55) | ESR1ESR2 | |
| SCHEMBL1359828 | 0.85 | ESR1 (0.56) | ESR1ESR2LTA4H | |
| SCHEMBL1357972 | 0.85 | HTT (0.56) | ESR1ESR2HTTLTA4H | |
| SCHEMBL4924892 | 0.84 | LTA4H (0.46) | ESR1ESR2HTTLTA4HMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221163-A1 | Selective Estrogen Receptor Modulators | ELI LILLY AND COMPANY | 2008-09-11 | — | — | US | disclosed |
| EP-1713820-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005073244-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221163-A1 | Selective Estrogen Receptor Modulators | GPER1, ESR2, ESR1 | ESR1 3/4885ESR2 2/4885HTT 4746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.