SCHEMBL4931363

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6919516	0.89	HDAC6 (0.81)	TP53HDAC6HDAC1HDAC8HDAC2
	SCHEMBL5013790	0.89	TP53 (1.00)	TP53HDAC6HDAC1HDAC8HDAC2
	SCHEMBL2829167	0.87	HDAC6 (1.00)	HDAC6HDAC1HDAC8HDAC2HDAC11
	SCHEMBL14260700	0.86	HDAC1 (0.80)	TP53HDAC6HDAC1HDAC8HDAC2
	SCHEMBL4931020	0.84	TP53 (0.72)	TP53HDAC6HDAC1HDAC11HDAC3
	SCHEMBL8292059	0.83	TP53 (0.67)	TP53HDAC6HDAC1HDAC8HDAC2
	SCHEMBL6570908	0.82	HDAC6 (1.00)	HDAC6HDAC1HDAC8HDAC2HDAC11
	SCHEMBL14260699	0.81	HDAC6 (0.58)	TP53HDAC6HDAC1HDAC8HDAC2
	SCHEMBL8291939	0.81	TP53 (0.68)	TP53HDAC6HDAC1HDAC2HDAC3
	SCHEMBL28024624	0.81	HDAC6 (0.77)	HDAC6HDAC1HDAC8HDAC2HDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.