SCHEMBL4931381

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4935092	0.84	HTR4 (0.43)	DYRK1ANTRK1HTR4IKBKBCHEK1
	SCHEMBL5171813	0.79	CHEK1 (0.43)	KMT2AHTR4HDAC3HDAC1HDAC2
	SCHEMBL4930520	0.79	NTRK1 (0.47)	CDK2CCNA1CCNA2GSK3BKMT2A
	SCHEMBL4925482	0.75	CDK2 (0.45)	CDK2CDK5CCNA1CCNT1CDK9
	SCHEMBL4933825	0.75	CDK2 (0.58)	CDK2CDK5CCNA1CCNT1CDK9
	Hydrochloric Acid SCHEMBL4934603	0.74	CDK2 (0.44)	CDK2CDK5CCNA1CCNT1CDK9
	SCHEMBL4931383	0.73	CCNA2 (0.47)	CDK2CDK5CCNA1CDK5R1CCNA2
	SCHEMBL4934595	0.72	HTR4 (0.48)	HTR4HDAC3HDAC1HDAC2HDAC6
	SCHEMBL4934641	0.72	DYRK1A (0.49)	CDK2CCNA2DYRK1AHTR4WNT1
	SCHEMBL4931765	0.70	MAPK1 (0.48)	KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.