Piceid

Piceid

SCHEMBL4931485

OC[C@H]1OC(Oc2cc(O)cc(C=Cc3ccc(O)cc3)c2)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 1.00
PTGS2 P35354 2/20 1.00
KDM4E B2RXH2 1/20 1.00
GAA P10253 1/20 1.00
MAPT P10636 1/20 1.00
G6PD P11413 1/20 1.00
MAPK1 P28482 1/20 1.00
ADRA1A P35348 1/20 1.00
TYR P14679 2/20 0.67
PTGS1 P23219 1/20 0.65
AKR1B1 P15121 1/20 0.60
DPP4 P27487 1/20 0.60
CDK5 Q00535 1/20 0.53
CDK5R1 Q15078 1/20 0.53
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA4 P22748 2/20 0.53
CA5A P35218 2/20 0.53
CA7 P43166 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piceid SCHEMBL3123046 1.00 POLB (1.00) POLBPTGS2KDM4EGAAMAPT
Piceid SCHEMBL14029474 1.00 POLB (1.00) POLBPTGS2KDM4EGAAMAPT
Piceid SCHEMBL20164198 1.00 POLB (1.00) POLBPTGS2KDM4EGAAMAPT
Piceid SCHEMBL20450473 1.00 POLB (1.00) POLBPTGS2KDM4EGAAMAPT
Piceid SCHEMBL13252338 1.00 POLB (1.00) POLBPTGS2KDM4EGAAMAPT
Piceid SCHEMBL10182561 1.00 POLB (1.00) POLBPTGS2KDM4EGAAMAPT
Piceid SCHEMBL16419687 1.00 POLB (1.00) POLBPTGS2KDM4EGAAMAPT
Piceid SCHEMBL10148943 1.00 POLB (1.00) POLBPTGS2KDM4EGAAMAPT
Piceid SCHEMBL22111468 1.00 POLB (1.00) POLBPTGS2KDM4EGAAMAPT
Piceid SCHEMBL3123021 1.00 POLB (1.00) POLBPTGS2KDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080139650-A1 Fungicidally Active Polymer Dispersions And Use Thereof CELANESE EMULSIONS GMBH (DE) 2008-06-12 US claimed
US-20080139650-A1 Fungicidally Active Polymer Dispersions And Use Thereof CELANESE EMULSIONS GMBH (DE) 2008-06-12 US disclosed
US-7189706-B2 C2,5′-disubstituted and N6,C2,5′-trisubstituted adenosine derivatives and pharmaceutical compositions containing them UNIVERSITEIT LEIDEN (NL) 2007-03-13 US disclosed
US-7084127-B2 C2,5′-disubstituted and N6, C2,5′-trisubstituted adenosine derivatives and their different uses UNIVERSITEIT LEIDEN (NL) 2006-08-01 US disclosed
US-20040132686-A1 C2,5'- disubstituted and N6, c2,5'- trisubstituted adenosine derivatives and their different uses UNIVERSITEIT LEIDEN (NL) 2004-07-08 US disclosed
US-20040127452-A1 C2,5'-disubstituted and N6,C2,5'-trisubstituted adenosine derivatives and pharmaceutical compositions containing them UNIVERSITEIT LEIDEN (NL) 2004-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040127452-A1 C2,5'-disubstituted and N6,C2,5'-trisubstituted adenosine derivatives and pharmaceutical compositions containing them ADORA2A, ADORA3, ADORA1 POLB 3148/4885PTGS2 1197/4885KDM4E 4105/4885
US-20080139650-A1 Fungicidally Active Polymer Dispersions And Use Thereof CBR3, CBR1, CYP3A4 POLB 2174/4885PTGS2 3728/4885KDM4E 1199/4885
US-20040132686-A1 C2,5'- disubstituted and N6, c2,5'- trisubstituted adenosine derivatives and their different uses ADORA2A, ADORA3, ADORA1 POLB 3119/4885PTGS2 1419/4885KDM4E 4299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.