Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | ACP1 | P24666 | 1/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922627 | 0.79 | DRD3 (0.63) | MEN1KMT2ADRD3HRH3DPP7 | |
| SCHEMBL5770043 | 0.79 | DRD3 (0.59) | MEN1KMT2ADRD3HRH3DPP7 | |
| SCHEMBL11722763 | 0.79 | DRD3 (0.59) | MEN1KMT2ADRD3HRH3ALDH1A1 | |
| SCHEMBL4932045 | 0.78 | DPP7 (0.58) | MEN1KMT2ADRD3ALDH1A1DPP7 | |
| SCHEMBL791880 | 0.78 | DRD3 (0.61) | MEN1KMT2ADRD3HRH3ACP1 | |
| SCHEMBL5884397 | 0.78 | DRD3 (0.57) | MEN1KMT2ADRD3HRH3ALDH1A1 | |
| SCHEMBL8673780 | 0.77 | POLB (0.59) | MEN1KMT2ADRD3HRH3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5753957 | 0.77 | DPP7 (0.56) | MEN1KMT2ADRD3ALDH1A1DPP7 | |
| SCHEMBL16583873 | 0.76 | SIGMAR1 (0.45) | MEN1KMT2ADRD3HRH3ACP1 | |
| SCHEMBL8560287 | 0.76 | DRD3 (0.58) | MEN1KMT2ADRD3HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1830978-B | Pyrazolo [4,3-c]-quinolin-3-one compound, preparation method and use thereof | INST PHARM & TOXICOLOGY AMMS | 2010-06-16 | — | — | CN | disclosed |
| US-20080076774-A1 | Kinase Modulators and Methods of Use | EXELIXIS, INC. (US) | 2008-03-27 | — | — | US | disclosed |
| CN-1830978-A | Pyrazolo [4,3c]-quinolin-3-one compound, prepn. method and use thereof | VENENUM MEDICINE RES INST OF M (CN) | 2006-09-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076774-A1 | Kinase Modulators and Methods of Use | AKT3, RPS6KA3, CDK3 | MEN1 2030/4885KMT2A 3849/4885DRD3 2434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.