SCHEMBL4932469

SCHEMBL4932469

Nc1ccc2c(c1N)Cc1ccccc1S2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
MAPT P10636 2/20 0.46
ALDH1A1 P00352 3/20 0.43
HPGD P15428 3/20 0.43
KDM4E B2RXH2 2/20 0.43
BLM P54132 1/20 0.40
LMNA P02545 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HTT P42858 1/20 0.36
ATM Q13315 1/20 0.36
BCHE P06276 3/20 0.32
ACHE P22303 3/20 0.32
NOX1 Q9Y5S8 2/20 0.32
CYP1A2 P05177 1/20 0.32
POLB P06746 1/20 0.32
CYP3A4 P08684 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
GAA P10253 1/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL88254 0.81 ALDH1A1 (0.46) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL9693608 0.77 MEN1 (0.43) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL15738070 0.76 MEN1 (0.41) MEN1KMT2AMAPTALDH1A1HPGD
Thioxanthene SCHEMBL8717 0.73 ALDH1A1 (0.61) MEN1KMT2AMAPTALDH1A1HPGD
Thioxanthene SCHEMBL29398766 0.73 ALDH1A1 (0.61) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL5606116 0.72 ALDH1A1 (0.44) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL137986 0.71 ALDH1A1 (0.43) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL29413862 0.71 ALDH1A1 (0.43) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL5695872 0.71 ALDH1A1 (0.43) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL2762892 0.71 MEN1 (0.37) MEN1KMT2AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0361377-B1 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1995-06-28 EP claimed
EP-0390992-B1 Aromatic polyimide double layered hollow filamentary membrane and process for producing same UBE INDUSTRIES (JP) 1994-06-01 EP claimed
US-5141642-A Separators for reverse osmosis, ultrafiltration, dehydration, heat and chemical resistance, strength, gas permeability UBE INDUSTRIES, LTD. (JP) 1992-08-25 US claimed
US-4997462-A Pervaporation method of selectively separating water from an organic material aqueous solution through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1991-03-05 US claimed
EP-0390992-A1 Aromatic polyimide double layered hollow filamentary membrane and process for producing same UBE INDUSTRIES, LTD. (JP) 1990-10-10 EP claimed
EP-0391699-A1 Pervaporation method of selectively separating water from an organic material aqueous solution through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-10-10 EP claimed
US-4959151-A Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1990-09-25 US claimed
EP-0361377-A2 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-04-04 EP claimed
US-7339009-B2 Cross-linked polyimide and method of making them GENERAL ELECTRIC COMPANY (US) 2008-03-04 US disclosed
US-20060135732-A1 Cross-linked polyimide and method of making them GENERAL ELECTRIC COMPANY 2006-06-22 US disclosed
EP-0361377-B1 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1995-06-28 EP disclosed
EP-0446947-B1 Gas separating asymmetric membrane UBE INDUSTRIES (JP) 1995-05-24 EP disclosed
EP-0390992-B1 Aromatic polyimide double layered hollow filamentary membrane and process for producing same UBE INDUSTRIES (JP) 1994-06-01 EP disclosed
US-5292963-A Continuous, polyimide separating membrane UBE INDUSTRIES, LTD. (JP) 1994-03-08 US disclosed
EP-0390992-A1 Aromatic polyimide double layered hollow filamentary membrane and process for producing same UBE INDUSTRIES, LTD. (JP) 1990-10-10 EP disclosed
EP-0391699-A1 Pervaporation method of selectively separating water from an organic material aqueous solution through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-10-10 EP disclosed
US-4959151-A Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES (JP) 1990-09-25 US disclosed
EP-0361377-A2 Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane UBE INDUSTRIES, LTD. (JP) 1990-04-04 EP disclosed
EP-0263212-A1 Method for removing water vapor from water vapor-containing gas UBE INDUSTRIES, LTD. (JP) 1988-04-13 EP disclosed
US-4718921-A Method for removing water vapor from water vapor-containing gas UBE INDUSTRIES, LTD. (JP) 1988-01-12 US disclosed