Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4932644 | 1.00 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ALMNAHDAC1 | |
| SCHEMBL4930171 | 0.92 | HDAC1 (0.51) | ALDH1A1MEN1KMT2ALMNAHDAC1 | |
| SCHEMBL4930166 | 0.92 | HDAC1 (0.51) | ALDH1A1MEN1KMT2ALMNAHDAC1 | |
| SCHEMBL4933474 | 0.91 | HDAC1 (0.57) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL4933463 | 0.91 | HDAC1 (0.57) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL4922675 | 0.88 | HDAC1 (0.52) | LMNAHDAC1HDAC2HDAC3HDAC8 | |
| SCHEMBL8291642 | 0.88 | HDAC1 (0.53) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL4930160 | 0.88 | HDAC2 (0.53) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL4930156 | 0.88 | HDAC2 (0.53) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL4922668 | 0.88 | HDAC1 (0.52) | LMNAHDAC1HDAC2HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | S*BIO PTE LTD. (SG) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | HDAC1, HDAC3, HDAC4 | ALDH1A1 1020/4885MEN1 2737/4885KMT2A 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.