Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 11/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.52 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 3/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4921889 | 0.90 | HDAC1 (0.53) | HDAC2HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL4933486 | 0.89 | HDAC2 (0.50) | HDAC2HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL4930697 | 0.88 | HDAC1 (0.52) | HDAC2HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL4931294 | 0.87 | HDAC1 (0.55) | HDAC2HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL4931762 | 0.87 | HDAC1 (0.51) | HDAC2HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL4928501 | 0.86 | HDAC1 (0.50) | HDAC2HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL4930143 | 0.86 | HDAC1 (0.50) | HDAC2HDAC1HDAC3HDAC8HDAC6 | |
| SCHEMBL4922709 | 0.85 | HDAC2 (0.49) | HDAC2HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL4929990 | 0.85 | HDAC1 (0.49) | HDAC2HDAC1HDAC3HDAC8HDAC4 | |
| SCHEMBL4929939 | 0.85 | HDAC1 (0.49) | HDAC2HDAC1HDAC3HDAC8HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | S*BIO PTE LTD. (SG) | 2008-03-20 | — | — | US | claimed |
| EP-1685094-A4 | ACYLUREA CONNECTED AND SULFONYLUREA CONNECTED HYDROXAMATES | S BIO PTE LTD (SG) | 2007-08-22 | — | — | EP | claimed |
| EP-1685094-A1 | ACYLUREA CONNECTED AND SULFONYLUREA CONNECTED HYDROXAMATES | S*Bio Pte Ltd (SG) | 2006-08-02 | — | — | EP | claimed |
| WO-2005040101-A1 | ACYLUREA CONNECTED AND SULFONYLUREA CONNECTED HYDROXAMATES | S*BIO PTE LTD (SG) | 2005-05-06 | — | — | WO | claimed |
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | S*BIO PTE LTD. (SG) | 2008-03-20 | — | — | US | disclosed |
| EP-1685094-A4 | ACYLUREA CONNECTED AND SULFONYLUREA CONNECTED HYDROXAMATES | S BIO PTE LTD (SG) | 2007-08-22 | — | — | EP | disclosed |
| EP-1685094-A1 | ACYLUREA CONNECTED AND SULFONYLUREA CONNECTED HYDROXAMATES | S*Bio Pte Ltd (SG) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005040101-A1 | ACYLUREA CONNECTED AND SULFONYLUREA CONNECTED HYDROXAMATES | S*BIO PTE LTD (SG) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | HDAC1, HDAC3, HDAC4 | HDAC2 10/4885HDAC1 1/4885HDAC3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.