Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 10/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4928501 | 0.90 | HDAC1 (0.50) | HDAC2HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL4933022 | 0.85 | HDAC2 (0.52) | HDAC2HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL4929990 | 0.84 | HDAC1 (0.49) | HDAC2HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL4929939 | 0.84 | HDAC1 (0.49) | HDAC2HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL4922244 | 0.84 | HDAC1 (0.47) | HDAC2HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL4925192 | 0.84 | LMNA (0.45) | HDAC2HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL4925750 | 0.84 | UTS2R (0.64) | UTS2R | |
| SCHEMBL4932493 | 0.84 | EGFR (0.47) | HDAC2HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL4933486 | 0.83 | HDAC2 (0.50) | HDAC2HDAC3HDAC1HDAC8HDAC4 | |
| SCHEMBL4930429 | 0.83 | HDAC1 (0.46) | HDAC2HDAC3HDAC1HDAC8HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | S*BIO PTE LTD. (SG) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070954-A1 | Acylurea Connected And Sulfonylurea Connected Hydroxamates | HDAC1, HDAC3, HDAC4 | HDAC2 10/4885HDAC3 2/4885HDAC1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.