Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 6/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 3/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4933529 | 1.00 | GHSR (0.54) | GHSRADRB1BCL2A1HTTPTPN11 | |
| SCHEMBL4801586 | 0.85 | HTT (0.46) | GHSRBCL2A1HTTPTPN11LMNA | |
| SCHEMBL4801584 | 0.85 | HTT (0.46) | GHSRBCL2A1HTTPTPN11LMNA | |
| SCHEMBL4216171 | 0.85 | HTT (0.46) | GHSRBCL2A1HTTPTPN11NOTUM | |
| SCHEMBL4216169 | 0.85 | HTT (0.46) | GHSRBCL2A1HTTPTPN11NOTUM | |
| Hydrochloric Acid SCHEMBL4219984 | 0.83 | HTT (0.45) | GHSRHTTPTPN11NOTUM | |
| Hydrochloric Acid SCHEMBL4219981 | 0.83 | HTT (0.45) | GHSRHTTPTPN11NOTUM | |
| SCHEMBL18013225 | 0.81 | BCL2A1 (0.66) | ADRB1BCL2A1HTTLMNAMAPT | |
| SCHEMBL4936462 | 0.81 | BCL2A1 (0.66) | ADRB1BCL2A1HTTLMNAMAPT | |
| SCHEMBL1471198 | 0.81 | NOTUM (0.52) | GHSRHTTNOTUMDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176856-A1 | Novel Alkyl Substituted Piperidine Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors | NEUROSEARCH A/S (DK) | 2008-07-24 | — | — | US | claimed |
| US-20080176856-A1 | Novel Alkyl Substituted Piperidine Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors | NEUROSEARCH A/S (DK) | 2008-07-24 | — | — | US | disclosed |
| EP-1761512-A1 | NOVEL ALKYL SUBSTITUTED PIPERAZINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2007-03-14 | — | — | EP | disclosed |
| WO-2005123707-A1 | NOVEL ALKYL SUBSTITUTED PIPERAZINE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176856-A1 | Novel Alkyl Substituted Piperidine Derivatives and Their Use as Monoamine Neurotransmitter Re-Uptake Inhibitors | SLC18A2, SLC6A2, SLC18A3 | GHSR 1655/4885ADRB1 88/4885BCL2A1 4197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.