Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4933877 | 0.80 | BCHE (0.53) | LMNASMN1; SMN2BCHEACHEALDH1A1 | |
| SCHEMBL28722124 | 0.78 | MAPT (0.52) | LMNASMN1; SMN2BCHEACHEALDH1A1 | |
| SCHEMBL4728480 | 0.74 | DRD4 (0.55) | LMNASMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL4929684 | 0.70 | MAPT (0.50) | LMNASMN1; SMN2BCHEACHEALDH1A1 | |
| SCHEMBL19741641 | 0.70 | CHRM2 (0.49) | SMN1; SMN2ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL16070776 | 0.70 | CHRM2 (0.49) | SMN1; SMN2ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL10672122 | 0.70 | CHRM2 (0.49) | SMN1; SMN2ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL524001 | 0.68 | TAAR1 (0.68) | LMNASMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL6244544 | 0.68 | POLB (0.61) | LMNASMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL12737571 | 0.68 | TAAR1 (0.68) | LMNASMN1; SMN2ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280933-A1 | BENZIMIDAZOLYL COMPOUNDS | EFREMOV IVAN | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280933-A1 | BENZIMIDAZOLYL COMPOUNDS | PAICS, TMBIM6, ABCG2 | LMNA 2469/4885SMN1; SMN2 478/4885BCHE 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.