Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 12/20 | 0.65 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | NMBR | P28336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825566 | 0.92 | TGM2 (0.77) | TGM2CTSLCTSBCTSSCTSK | |
| SCHEMBL9825541 | 0.84 | TGM2 (0.64) | TGM2CTSLCTSBCTSSCTSK | |
| SCHEMBL9825709 | 0.83 | TGM2 (0.84) | TGM2CTSLCTSBCTSSCTSK | |
| SCHEMBL4934790 | 0.82 | TGM2 (0.71) | TGM2CTSLCTSBCTSSCTSK | |
| SCHEMBL4934255 | 0.80 | TGM2 (0.75) | TGM2CTSLCTSBCTSSCTSK | |
| SCHEMBL9825687 | 0.80 | TGM2 (0.84) | TGM2CTSLCTSBCTSSCTSK | |
| SCHEMBL9825778 | 0.80 | TGM2 (0.84) | TGM2CTSLCTSBCTSSCTSK | |
| SCHEMBL4934172 | 0.80 | TGM2 (0.83) | TGM2CTSLCTSBCTSSCTSK | |
| SCHEMBL9825174 | 0.80 | TGM2 (0.83) | TGM2CTSLCTSBCTSSCTSK | |
| SCHEMBL13934076 | 0.79 | TGM2 (1.00) | TGM2CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080299170-A1 | Medical Devices and Coatings Therefor | ASTON UNIVERSITY (GB) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080299170-A1 | Medical Devices and Coatings Therefor | F8, HABP2, TFPI | TGM2 16/4885CTSL 104/4885CTSB 683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.