Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRE | P78334 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31609494 | 1.00 | ALDH1A1 (0.50) | ALDH1A1ACHEGPR3HSD17B10GABRA1 | |
| SCHEMBL10734292 | 0.79 | PARP1 (0.62) | ALDH1A1GPR3HSD17B10KDM4EAURKA | |
| SCHEMBL29601450 | 0.75 | PARP1 (0.67) | ALDH1A1ACHEGPR3HSD17B10GABRA1 | |
| SCHEMBL29568550 | 0.75 | PARP1 (0.67) | ALDH1A1ACHEGPR3HSD17B10GABRA1 | |
| SCHEMBL1009117 | 0.75 | PARP1 (0.67) | ALDH1A1ACHEGPR3HSD17B10GABRA1 | |
| SCHEMBL29506294 | 0.74 | ALDH1A1 (0.48) | ALDH1A1ACHEGPR3HSD17B10GABRA1 | |
| SCHEMBL6689216 | 0.74 | ALDH1A1 (0.48) | ALDH1A1ACHEGPR3HSD17B10GABRA1 | |
| SCHEMBL29277816 | 0.73 | PARP1 (0.65) | ALDH1A1ACHEGPR3HSD17B10GABRA1 | |
| SCHEMBL79405 | 0.72 | ALDH1A1 (0.50) | ALDH1A1ACHEGPR3HSD17B10GABRA1 | |
| Carbazole SCHEMBL16505004 | 0.70 | ALDH1A1 (0.67) | ALDH1A1ACHEGPR3HSD17B10GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130115133-A1 | INACTIVATION OF MICROORGANISMS WITH MULTIDRUG RESISTANCE INHIBITORS AND PHENOTHIAZINIUMS | THE GENERAL HOSPITAL CORPORATION (US) | 2013-05-09 | — | — | US | claimed |
| US-20080166304-A1 | Inactivation of Microorganisms With Multidrug Resistance Inhibitors and Phenothiaziniums | THE GENERAL HOSPITAL CORPOARTION (US) | 2008-07-10 | — | — | US | claimed |
| WO-2006034219-A2 | INACTIVATION OF MICROORGANISMS WITH MULTIDRUG RESISTANCE INHIBITORS AND PHENOTHIAZINIUMS | THE GENERAL HOSPITAL CORPORATION (US) | 2006-03-30 | — | — | WO | claimed |
| US-20130115133-A1 | INACTIVATION OF MICROORGANISMS WITH MULTIDRUG RESISTANCE INHIBITORS AND PHENOTHIAZINIUMS | THE GENERAL HOSPITAL CORPORATION (US) | 2013-05-09 | — | — | US | disclosed |
| US-20080166304-A1 | Inactivation of Microorganisms With Multidrug Resistance Inhibitors and Phenothiaziniums | THE GENERAL HOSPITAL CORPOARTION (US) | 2008-07-10 | — | — | US | disclosed |
| WO-2006034219-A2 | INACTIVATION OF MICROORGANISMS WITH MULTIDRUG RESISTANCE INHIBITORS AND PHENOTHIAZINIUMS | THE GENERAL HOSPITAL CORPORATION (US) | 2006-03-30 | — | — | WO | disclosed |