Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.60 |
| ▸ | POLA1 | P09884 | 2/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5187388 | 1.00 | PDE3A (0.60) | PDE3APDE4DSLC29A1POLA1ITGB3 | |
| SCHEMBL4942006 | 1.00 | PDE3A (0.60) | PDE3APDE4DSLC29A1POLA1ITGB3 | |
| SCHEMBL4935081 | 1.00 | PDE3A (0.60) | PDE3APDE4DSLC29A1POLA1ITGB3 | |
| SCHEMBL5188355 | 1.00 | PDE3A (0.60) | PDE3APDE4DSLC29A1POLA1ITGB3 | |
| SCHEMBL4938679 | 1.00 | PDE3A (0.60) | PDE3APDE4DSLC29A1POLA1ITGB3 | |
| SCHEMBL4941183 | 1.00 | PDE3A (0.60) | PDE3APDE4DSLC29A1POLA1ITGB3 | |
| SCHEMBL4939657 | 1.00 | PDE3A (0.60) | PDE3APDE4DSLC29A1POLA1ITGB3 | |
| SCHEMBL4940086 | 1.00 | PDE3A (0.60) | PDE3APDE4DSLC29A1POLA1ITGB3 | |
| SCHEMBL4938641 | 0.99 | PDE3A (0.61) | PDE3APDE4DSLC29A1POLA1ITGB3 | |
| SCHEMBL4931963 | 0.96 | PDE3A (0.62) | PDE3APDE4DSLC29A1POLA1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080103110-A1 | Compounds | DRUG DISCOVERY LABORATORY AS (NO) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103110-A1 | Compounds | ATIC, CDA, PAICS | PDE3A 2090/4885PDE4D 2811/4885SLC29A1 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.