Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | CDC25C | P30307 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541161 | 0.85 | ALDH1A1 (0.71) | KDM4EPOLBATMALDH1A1TSHR | |
| SCHEMBL20561691 | 0.84 | KDM4E (0.62) | KDM4EPOLBATMALDH1A1TSHR | |
| SCHEMBL6318035 | 0.83 | KDM4E (0.70) | KDM4EPOLBATMALDH1A1TSHR | |
| SCHEMBL619175 | 0.81 | TSHR (0.69) | KDM4EPOLBATMALDH1A1TSHR | |
| SCHEMBL4904098 | 0.81 | TSHR (0.73) | KDM4EPOLBATMALDH1A1TSHR | |
| SCHEMBL4858499 | 0.81 | KDM4E (0.58) | KDM4EPOLBATMALDH1A1TSHR | |
| SCHEMBL11690383 | 0.80 | ALDH1A1 (0.74) | KDM4EPOLBATMALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL6379948 | 0.80 | TSHR (0.67) | KDM4EPOLBATMALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL29471312 | 0.78 | SCN1A (0.61) | KDM4EPOLBATMALDH1A1TSHR | |
| SCHEMBL24013287 | 0.77 | ALDH1A1 (0.63) | KDM4EPOLBATMALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080032409-A1 | FLUORESCENT BIOMOLECULE LABELING REAGENTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-02-07 | — | — | US | disclosed |
| US-20080032409-A1 | FLUORESCENT BIOMOLECULE LABELING REAGENTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-02-07 | — | — | US | disclosed |
| US-20080032409-A1 | FLUORESCENT BIOMOLECULE LABELING REAGENTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080032409-A1 | FLUORESCENT BIOMOLECULE LABELING REAGENTS | PAICS, IPMK, IK | KDM4E 3921/4885POLB 237/4885ATM 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.