Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CSK | P41240 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4935136 | 1.00 | HDAC8 (0.55) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL4934979 | 0.82 | CSK (0.60) | HDAC8CA1CA2CA12CA9 | |
| SCHEMBL4934991 | 0.82 | CSK (0.60) | HDAC8CA1CA2CA12CA9 | |
| SCHEMBL21689987 | 0.82 | ENPP2 (0.59) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL5678587 | 0.78 | MAPT (0.59) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL4934030 | 0.78 | CSK (0.56) | HDAC8CSKHPGD | |
| SCHEMBL4934022 | 0.78 | CSK (0.56) | HDAC8CSKHPGD | |
| SCHEMBL27828203 | 0.78 | ENPP2 (0.54) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL4415174 | 0.77 | ENPP2 (0.60) | HDAC8HDAC3HDAC6HDAC1HDAC2 | |
| SCHEMBL4930575 | 0.77 | CSK (0.55) | HDAC8HDAC3HDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132539-A1 | Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative | KUREHA CORPORATION (JP) | 2008-06-05 | — | — | US | disclosed |
| EP-1707560-A1 | HYDROXAMIC ACID DERIVATIVE AND AGE GENERATION INHIBITOR CONTAINING THE DERIVATIVE | Kureha Corporation (JP) | 2006-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132539-A1 | Hydroxamic Acid Derivative And Age Generation Inhibitor Containing The Derivative | HDAC5, HDAC1, HDAC9 | HDAC8 4/4885HDAC3 17/4885HDAC6 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.