Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.68 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.68 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4932782 | 0.92 | CHRNB2 (0.61) | CHRNB2CHRNA4LTA4HPTGS2CHRNB4 | |
| SCHEMBL3442965 | 0.85 | CHRNB2 (0.66) | CHRNB2CHRNA4LTA4HPTGS2CHRNB4 | |
| SCHEMBL3975841 | 0.85 | CHRNB2 (0.66) | CHRNB2CHRNA4LTA4HPTGS2CHRNB4 | |
| SCHEMBL1735199 | 0.84 | CHRNB2 (0.74) | CHRNB2CHRNA4CHRNB4CHRNA3HPGD | |
| SCHEMBL28505899 | 0.84 | CHRNB2 (0.64) | CHRNB2CHRNA4LTA4HPTGS2CHRNB4 | |
| SCHEMBL4933227 | 0.82 | KCNH2 (0.63) | LTA4HPTGS2MAPTKCNH2ALDH1A1 | |
| SCHEMBL15498199 | 0.82 | CHRNB2 (0.73) | CHRNB2CHRNA4LTA4HPTGS2CHRNB4 | |
| SCHEMBL3213420 | 0.81 | CHRNB2 (1.00) | CHRNB2CHRNA4LTA4HPTGS2CHRNB4 | |
| SCHEMBL7042749 | 0.80 | CHRNB2 (0.67) | CHRNB2CHRNA4LTA4HPTGS2CHRNB4 | |
| SCHEMBL1025947 | 0.79 | CHRNB2 (0.66) | CHRNB2CHRNA4LTA4HPTGS2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | ACADEMIA SINICA (TW) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | BCL9, MCL1, BCL9L | CHRNB2 4473/4885CHRNA4 3797/4885LTA4H 3902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.