Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3507116 | 1.00 | — | — | |
| SCHEMBL7188040 | 1.00 | TSHR (0.42) | TSHRTHRBALDH3A1HSD17B10TP53 | |
| SCHEMBL3409351 | 1.00 | TSHR (0.42) | TSHRTHRBALDH3A1HSD17B10TP53 | |
| SCHEMBL9451397 | 1.00 | TSHR (0.42) | TSHRTHRBALDH3A1HSD17B10TP53 | |
| SCHEMBL7133112 | 1.00 | TSHR (0.42) | TSHRTHRBALDH3A1HSD17B10TP53 | |
| SCHEMBL6580529 | 1.00 | TSHR (0.42) | TSHRTHRBALDH3A1HSD17B10TP53 | |
| SCHEMBL6241827 | 1.00 | TSHR (0.42) | TSHRTHRBALDH3A1HSD17B10TP53 | |
| SCHEMBL4284127 | 1.00 | TSHR (0.42) | TSHRTHRBALDH3A1HSD17B10TP53 | |
| SCHEMBL1873873 | 1.00 | TSHR (0.42) | TSHRTHRBALDH3A1HSD17B10TP53 | |
| SCHEMBL4958752 | 1.00 | TSHR (0.42) | TSHRTHRBALDH3A1HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0631982-B1 | Silica based aggregates, elastomers reinforced therewith and tire with tread thereof | GOODYEAR TIRE & RUBBER (US) | 2002-01-09 | — | — | EP | claimed |
| US-6068694-A | Silica based aggregates, elastomers reinforced therewith and tire with tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-05-30 | — | — | US | claimed |
| EP-0631982-A2 | Silica based aggregates, elastomers reinforced therewith and tire with tread thereof | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1995-01-04 | — | — | EP | claimed |
| EP-3162799-B1 | FLUOROALKYLATING AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2021-03-10 | — | — | EP | disclosed |
| US-10696640-B2 | Fluoroalkylating agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2020-06-30 | — | — | US | disclosed |
| CN-106573896-B | Fluoroalkylating agents | KUMIAI CHEMICAL INDUSTRY CO.,LTD. (JP) | 2019-11-01 | — | — | CN | disclosed |
| US-20190233380-A1 | FLUOROALKYLATING AGENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-08-01 | — | — | US | disclosed |
| US-10308613-B2 | Fluoroalkylating agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-06-04 | — | — | US | disclosed |
| US-20170197920-A1 | FLUOROALKYLATING AGENT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-07-13 | — | — | US | disclosed |
| EP-3162799-A1 | FLUOROALKYLATING AGENT | Ihara Chemical Industry Co., Ltd. (JP) | 2017-05-03 | — | — | EP | disclosed |
| WO-2015132802-A2 | A PROCESS FOR SYNTHESIS OF SINGLE LAYER METAL SHEETS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-09-11 | — | — | WO | disclosed |
| EP-0211065-B1 | CORROSION INHIBITOR FOR HIGH DENSITY BRINES | THE DOW CHEMICAL COMPANY (US) | 1990-07-18 | — | — | EP | disclosed |
| US-4877899-A | LARVACIDES, INSECTICIDES; SULFUR-SUBSTITUTED ALKENYL COMPOUNDS | SANDOZ LTD. (CH) | 1989-10-31 | — | — | US | disclosed |
| US-4801394-A | TRIAZINE-DITHIOL COMPOUND FOR COATING HEAT EXCHANGE TUBES | Nakamura, Yoshiro (JP) | 1989-01-31 | — | — | US | disclosed |
| EP-0211065-A4 | CORROSION INHIBITOR FOR HIGH DENSITY BRINES. | DOW CHEMICAL CO (US) | 1988-07-29 | — | — | EP | disclosed |
| US-4668666-A | INSECTICIDES | ADAMS VETERINARY RESEARCH LABORATORIES (US) | 1987-05-26 | — | — | US | disclosed |
| EP-0211065-A1 | CORROSION INHIBITOR FOR HIGH DENSITY BRINES. | DOW CHEMICAL CO (US) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986004634-A1 | CORROSION INHIBITOR FOR HIGH DENSITY BRINES | THE DOW CHEMICAL COMPANY (US) | 1986-08-14 | — | — | WO | disclosed |
| US-4601933-A | TRIAZINEDITHIOL | Nakamura, Yoshiro (JP) | 1986-07-22 | — | — | US | disclosed |
| WO-1986003374-A1 | LONG-ACTING PYRETHRUM/PYRETHROID BASED PESTICIDES WITH SILICONE STABILIZERS | ADAMS VETERINARY RESEARCH LABORATORIES, INC. (US) | 1986-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308613-B2 | Fluoroalkylating agent | AFF1, AFF4, AFF2 | TSHR 270/4885THRB 3128/4885ALDH3A1 2205/4885 |
| US-10696640-B2 | Fluoroalkylating agent | AFF1, AFF4, AFF2 | TSHR 270/4885THRB 3128/4885ALDH3A1 2205/4885 |
| US-20190233380-A1 | FLUOROALKYLATING AGENT | AFF1, AFF4, AFF2 | TSHR 270/4885THRB 3128/4885ALDH3A1 2205/4885 |
| US-20170197920-A1 | FLUOROALKYLATING AGENT | AFF1, AFF4, AFF2 | TSHR 270/4885THRB 3128/4885ALDH3A1 2205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.