Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944689 | 1.00 | PRNP (0.51) | PRNPRXFP1NR4A1NR4A2NR4A3 | |
| SCHEMBL28967943 | 0.95 | PRNP (0.48) | PRNPRXFP1NR4A1NR4A2NR4A3 | |
| SCHEMBL14885642 | 0.90 | PRNP (0.57) | PRNPRXFP1NR4A1NR4A2NR4A3 | |
| SCHEMBL29589251 | 0.88 | ALDH1A1 (0.48) | PRNPRXFP1NR4A1NR4A2NR4A3 | |
| SCHEMBL300219 | 0.88 | ALDH1A1 (0.48) | PRNPRXFP1NR4A1NR4A2NR4A3 | |
| SCHEMBL31626799 | 0.88 | ALDH1A1 (0.48) | PRNPRXFP1NR4A1NR4A2NR4A3 | |
| Ammonia Solution, Strong SCHEMBL30382110 | 0.86 | MAPT (0.47) | PRNPRXFP1NR4A1NR4A2NR4A3 | |
| SCHEMBL28533855 | 0.86 | MAPT (0.47) | PRNPRXFP1NR4A1NR4A2NR4A3 | |
| SCHEMBL31083578 | 0.86 | NR4A1 (0.54) | PRNPRXFP1NR4A1NR4A2NR4A3 | |
| SCHEMBL5866499 | 0.86 | NR4A1 (0.54) | PRNPRXFP1NR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458954-B | Condensed fluorene derivative containing heterocycle | SFC株式会社 | 2022-06-28 | — | — | CN | disclosed |
| WO-2022125736-A1 | A TAUTOMERIC LIGAND ENABLES BIOMIMETIC C-H HYDROXYLATION WITH MOLECULAR OXYGEN | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-06-16 | — | — | WO | disclosed |
| EP-3160972-B1 | EXTENDED NON-LINEAR ACENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2019-07-24 | — | — | EP | disclosed |
| EP-3160972-B1 | EXTENDED NON-LINEAR ACENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2019-07-24 | — | — | EP | disclosed |
| US-20170162805-A1 | EXTENDED NON-LINEAR ACENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2017-06-08 | — | — | US | disclosed |
| US-20170162805-A1 | EXTENDED NON-LINEAR ACENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2017-06-08 | — | — | US | disclosed |
| US-20170162805-A1 | EXTENDED NON-LINEAR ACENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2017-06-08 | — | — | US | disclosed |
| EP-3160972-A1 | EXTENDED NON-LINEAR ACENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS | Merck Patent GmbH (DE) | 2017-05-03 | — | — | EP | disclosed |
| WO-2016000804-A1 | EXTENDED NON-LINEAR ACENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2016-01-07 | — | — | WO | disclosed |
| WO-2016000804-A1 | EXTENDED NON-LINEAR ACENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS | MERCK PATENT GMBH (DE) | 2016-01-07 | — | — | WO | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| EP-0945450-A1 | FUSED HETEROCYCLIC BENZENECARBOXYLIC ACID AMIDE DERIVATIVES AND PGD2 ANTAGONISTS CONTAINING THE SAME | SHIONOGI & CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| US-5391567-A | Oral administeration | MACROCHEM CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |
| US-5344941-A | Treatment of osteoporosis | MACROCHEM CORPORATION | 1994-09-06 | — | — | US | disclosed |
| EP-0259168-B1 | NEW WATER-SOLUBLE SALTS OF THIONAPTHENE-2-CARBOXYLIC ACID | Macrochem Corporation (US) | 1991-12-11 | — | — | EP | disclosed |
| EP-0259168-A1 | New water-soluble salts of thionapthene-2-carboxylic acid | Macrochem Corporation (US) | 1988-03-09 | — | — | EP | disclosed |
| US-4432986-A | N-(TETRAZOL-5-YL)-(DIBENZOTHIOPHENE-, OR DIBENZOFURAN-, OR 1,3-BEZODIOXOLE-, OR NAPHTHALENE-)-4-CARBOXAMIDE | RIKER LABORATORIES, INC. (US) | 1984-02-21 | — | — | US | disclosed |
| US-4185108-A | INDOLE OR CARBAZOLE CARBOXYLIC ACIDS | WESTWOOD PHARMACEUTICALS INC. (US) | 1980-01-22 | — | — | US | disclosed |
| US-4125621-A | THIOXANTHENE-9-ONES | BRISTOL-MYERS COMPANY (US) | 1978-11-14 | — | — | US | disclosed |
| US-4101668-A | BENZOTHIOPHENE AND DIBENZOTHIOPHENE CARBOXYLIC ACIDS | BRISTOL-MYERS COMPANY (US) | 1978-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170162805-A1 | EXTENDED NON-LINEAR ACENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS | ACE, ACE2, ECE2 | PRNP 1468/4885RXFP1 3742/4885NR4A1 2225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.