Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11640066 | 0.84 | MAPT (0.53) | MAPTNPSR1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4940323 | 0.80 | MAPT (0.58) | MAPTLMNANPSR1ALDH1A1HDAC3 | |
| SCHEMBL3434565 | 0.77 | MAPT (0.56) | MAPTLMNANPSR1ALDH1A1MEN1 | |
| SCHEMBL11318988 | 0.77 | MAPT (0.46) | MAPTNPSR1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2450680 | 0.76 | CYP1A2 (0.65) | MAPTLMNANPSR1ALDH1A1CYP1A2 | |
| SCHEMBL4939290 | 0.75 | NPSR1 (0.53) | MAPTLMNANPSR1ALDH1A1CYP1A2 | |
| SCHEMBL4937220 | 0.75 | KMT2A (0.55) | MAPTLMNANPSR1ALDH1A1HTT | |
| SCHEMBL16263502 | 0.74 | HPGD (0.42) | LMNAALDH1A1HDAC1HDAC6MEN1 | |
| SCHEMBL11140844 | 0.73 | CA12 (0.48) | NPSR1HTTCYP1A2CYP3A4HDAC3 | |
| SCHEMBL9504490 | 0.73 | MAPT (0.62) | MAPTLMNANPSR1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080308492-A1 | Filter Medium for Technical Applications, and Method for the Production Thereof | MAHLE INTERNATIONAL GMBH (DE) | 2008-12-18 | — | — | US | claimed |
| US-20080308492-A1 | Filter Medium for Technical Applications, and Method for the Production Thereof | MAHLE INTERNATIONAL GMBH (DE) | 2008-12-18 | — | — | US | disclosed |