Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3434565 | 0.88 | MAPT (0.56) | MAPTPOLBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL11640066 | 0.81 | MAPT (0.53) | MAPTPOLBALDH1A1NPSR1KMT2A | |
| SCHEMBL4935771 | 0.80 | MAPT (0.55) | MAPTSMN1; SMN2LMNAALDH1A1NPSR1 | |
| SCHEMBL4935717 | 0.79 | APEX1 (0.58) | MAPTPOLBLMNAALDH1A1GAA | |
| SCHEMBL4939290 | 0.78 | NPSR1 (0.53) | MAPTPOLBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9504490 | 0.76 | MAPT (0.62) | MAPTSMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL11141900 | 0.76 | POLB (0.54) | MAPTPOLBSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL2450680 | 0.76 | CYP1A2 (0.65) | MAPTPOLBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL20741156 | 0.75 | POLB (0.61) | MAPTPOLBALDH1A1GAATSHR | |
| SCHEMBL4936197 | 0.75 | MAPT (0.50) | MAPTPOLBLMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080308492-A1 | Filter Medium for Technical Applications, and Method for the Production Thereof | MAHLE INTERNATIONAL GMBH (DE) | 2008-12-18 | — | — | US | claimed |
| US-20080308492-A1 | Filter Medium for Technical Applications, and Method for the Production Thereof | MAHLE INTERNATIONAL GMBH (DE) | 2008-12-18 | — | — | US | disclosed |