Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 18/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3588181 | 0.83 | SLC6A7 (0.72) | SLC6A7SLC6A3RXRARXRBALDH1A1 | |
| SCHEMBL4396815 | 0.73 | SLC6A7 (0.72) | SLC6A7SLC6A3ALDH1A1TSHR | |
| SCHEMBL3583118 | 0.67 | SLC6A7 (0.75) | SLC6A7SLC6A3ALDH1A1TSHR | |
| SCHEMBL3779038 | 0.66 | SLC6A7 (0.79) | SLC6A7SLC6A3ALDH1A1TSHR | |
| SCHEMBL3577951 | 0.66 | SLC6A7 (0.81) | SLC6A7ALDH1A1TSHR | |
| SCHEMBL3578242 | 0.65 | SLC6A7 (1.00) | SLC6A7SLC6A3ALDH1A1TSHR | |
| SCHEMBL3575523 | 0.64 | SLC6A7 (0.92) | SLC6A7SLC6A3ALDH1A1TSHR | |
| SCHEMBL3578676 | 0.63 | SLC6A7 (0.83) | SLC6A7ALDH1A1TSHR | |
| SCHEMBL3576023 | 0.63 | SLC6A7 (0.61) | SLC6A7ALDH1A1TSHR | |
| SCHEMBL3576021 | 0.63 | SLC6A7 (0.61) | SLC6A7ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893212-A2 | MULTICYCLIC COMPOUNDS AND METHODS OF THEIR USE | Lexicon Pharmaceuticals, Inc. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006124748-A2 | MULTICYCLIC COMPOUNDS AND METHODS OF THEIR USE | LEXICON GENETICS INCORPORATED (US) | 2006-11-23 | — | — | WO | disclosed |