SCHEMBL493645

SCHEMBL493645

CCCC(=O)OC(CC(=O)OCC)(CC(=O)OCC)C(=O)OCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
GAA P10253 2/20 0.39
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
TRPA1 O75762 1/20 0.36
CYP1A2 P05177 1/20 0.36
LMNA P02545 2/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
PKM P14618 2/20 0.33
KDM4E B2RXH2 1/20 0.33
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
MAPT P10636 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CYP4F2 P78329 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8109883 0.88 DGKA (0.44) ALDH1A1GAACYP1A2LMNATSHR
SCHEMBL2729336 0.87 DGKA (0.47) ALDH1A1GAACYP1A2LMNATSHR
SCHEMBL28679681 0.87 DGKA (0.47) ALDH1A1GAACYP1A2LMNATSHR
SCHEMBL28665409 0.87 DGKA (0.47) ALDH1A1GAACYP1A2LMNATSHR
SCHEMBL7990802 0.87 DGKA (0.47) ALDH1A1GAACYP1A2LMNATSHR
SCHEMBL28666753 0.87 DGKA (0.47) ALDH1A1GAACYP1A2LMNATSHR
SCHEMBL2730465 0.87 DGKA (0.47) ALDH1A1GAACYP1A2LMNATSHR
SCHEMBL8104078 0.87 DGKA (0.47) ALDH1A1GAACYP1A2LMNATSHR
SCHEMBL27176324 0.86 GAA (0.36) ALDH1A1GAAMGAMSIMGAM2
SCHEMBL27708323 0.85 DGKA (0.46) ALDH1A1GAACYP1A2LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3253852-B1 USE OF A HYDROCARBYL-SUBSTITUTED SALICYLIC ACID DETERGENT AS AN INHIBITOR OF LEAD CORROSION CASTROL LTD (GB) 2024-06-19 EP claimed
EP-3253853-B1 USE OF A BORON-CONTAINING ADDITIVE AS AN INHIBITOR OF LEAD CORROSION CASTROL LTD (GB) 2021-07-21 EP claimed
US-10982166-B2 Use of a boron-containing additive as an inhibitor of lead corrosion CASTROL LIMITED (GB) 2021-04-20 US claimed
US-10907111-B2 Use of a hydrocarbyl-substituted salicylic acid detergent as an inhibitor of lead corrosion CASTROL LIMITED (GB) 2021-02-02 US claimed
EP-3320062-A1 USES AND COMPOSITIONS Castrol Limited (GB) 2018-05-16 EP claimed
CN-107873048-A Purposes of the salicylic acid detersive of alkyl substitution as lead corrosion inhibitor 卡斯特罗尔有限公司 2018-04-03 CN claimed
CN-107636130-A Use of boron-containing additives as lead corrosion inhibitors 卡斯特罗尔有限公司 2018-01-26 CN claimed
US-20180023019-A1 Use of a Boron-Containing Additive as an Inhibitor of Lead Corrosion CASTROL LIMITED (GB) 2018-01-25 US claimed
US-20180010062-A1 Use of a Hydrocarbyl-Substituted Salicylic Acid Detergent as an Inhibitor of Lead Corrosion CASTROL LIMITED (GB) 2018-01-11 US claimed
WO-2017005865-A1 USES AND COMPOSITIONS CASTROL LIMITED (GB) 2017-01-12 WO claimed
WO-2016124291-A1 USE OF A HYDROCARBYL-SUBSTITUTED SALICYLIC ACID DETERGENT AS AN INHIBITOR OF LEAD CORROSION CASTROL LIMITED (GB) 2016-08-11 WO claimed
WO-2016124292-A1 USE OF A BORON-CONTAINING ADDITIVE AS AN INHIBITOR OF LEAD CORROSION CASTROL LIMITED (GB) 2016-08-11 WO claimed
EP-2633009-A1 NON-AQUEOUS LUBRICANT AND FUEL COMPOSITIONS COMPRISING FATTY ACID ESTERS OF HYDROXY- CARBOXYLIC ACIDS, AND USES THEREOF Castrol Limited (GB) 2013-09-04 EP claimed
WO-2012056191-A1 NON-AQUEOUS LUBRICANT AND FUEL COMPOSITIONS COMPRISING FATTY ACID ESTERS OF HYDROXY- CARBOXYLIC ACIDS, AND USES THEREOF CASTROL LIMITED (GB) 2012-05-03 WO claimed
EP-3253852-B1 USE OF A HYDROCARBYL-SUBSTITUTED SALICYLIC ACID DETERGENT AS AN INHIBITOR OF LEAD CORROSION CASTROL LTD (GB) 2024-06-19 EP disclosed
CN-117838935-B Drug-coated balloon catheter and preparation method thereof 惠凯医疗科技(苏州)有限公司 2024-05-24 CN disclosed
CN-117838935-A Drug-coated balloon catheter and preparation method thereof 惠凯医疗科技(苏州)有限公司 2024-04-09 CN disclosed
WO-2005034816-A1 BIOABSORBABLE PUTTY-LIKE HEMOSTATIC IMPLANTS ORTHO THERAPEUTICS, LLC. (US) 2005-04-21 WO disclosed
US-20050065214-A1 Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects ABYRX, INC. 2005-03-24 US disclosed
US-5556905-A POLYLACTONES PLASTICIZED WITH CITRIC ACID ESTERS REILLY INDUSTRIES, INC. (US) 1996-09-17 US disclosed