⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28343355 | 0.92 | ADH1B (0.42) | — | |
| SCHEMBL10749074 | 0.92 | — | — | |
| SCHEMBL11861192 | 0.89 | EPHX1 (0.54) | — | |
| SCHEMBL6556648 | 0.89 | EPHX1 (0.54) | — | |
| SCHEMBL9485078 | 0.89 | EPHX1 (0.54) | — | |
| SCHEMBL3347455 | 0.89 | EPHX1 (0.54) | — | |
| SCHEMBL17873409 | 0.89 | EPHX1 (0.54) | — | |
| SCHEMBL14237059 | 0.89 | EPHX1 (0.54) | — | |
| SCHEMBL2841962 | 0.89 | EPHX1 (0.54) | — | |
| SCHEMBL9008392 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114561359-A | Culture medium for culturing recurrent gastric cancer organoid and application thereof | 上海诺典生物科技有限公司 | 2022-05-31 | — | — | CN | claimed |
| US-5013751-A | (+) Suprofen esters and amides as opthalmic anti-inflammatory agents | ALCON LABORATORIES, INC. (US) | 1991-05-07 | — | — | US | claimed |
| US-4988728-A | Suprofen derivatives as antiinflammatory agents for eyes | ALCON LABORATORIES, INC. (US) | 1991-01-29 | — | — | US | claimed |
| US-11896678-B2 | Compositions and methods for treatment of peroxisome proliferator-activated receptor gamma (PPARG) activated cancer | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-02-13 | — | — | US | disclosed |
| CN-114561359-A | Culture medium for culturing recurrent gastric cancer organoid and application thereof | 上海诺典生物科技有限公司 | 2022-05-31 | — | — | CN | disclosed |
| US-10995091-B2 | CXCR4 receptor antagonists | PROXIMAGEN LLC (US) | 2021-05-04 | — | — | US | disclosed |
| US-20200179534-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA (PPARG) ACTIVATED CANCER | THE BROAD INSTITUTE, INC. (US) | 2020-06-11 | — | — | US | disclosed |
| EP-3600353-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA (PPARG) ACTIVATED CANCER | The Broad Institute, Inc. (US) | 2020-02-05 | — | — | EP | disclosed |
| CN-106018624-B | The HPLC detection methods of food nitrite nitramine | 曲阜师范大学 | 2018-10-12 | — | — | CN | disclosed |
| WO-2018183580-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA (PPARG) ACTIVATED CANCER | THE BROAD INSTITUTE, INC (US) | 2018-10-04 | — | — | WO | disclosed |
| US-20170226106-A1 | CXCR4 Receptor Antagonists | PROXIMAGEN, LLC | 2017-08-10 | — | — | US | disclosed |
| US-6838566-B2 | Salts of HMG-CoA reductase inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2005-01-04 | — | — | US | disclosed |
| EP-1466886-A2 | New salts of HMG-CoA reductase inhibitors | Lek Pharmaceutical and Chemical Co. D.D. (SI) | 2004-10-13 | — | — | EP | disclosed |
| EP-1114021-B1 | NEW SALTS OF HMG-CoA REDUCTASE INHIBITORS | LEK TOVARNA FARMACEVTSKIH (SI) | 2004-07-14 | — | — | EP | disclosed |
| US-20030120086-A1 | New salts of HMG-CoA reductase inhibitors | LEK PHARMACEUTICALS D.D. (SI) | 2003-06-26 | — | — | US | disclosed |
| US-6583295-B1 | Amine salts of such as lovastatin, pravastatin, simvastatin, mevastatin or atorvastatin | LEK PHARMACEUTICALS D.D. (SI) | 2003-06-24 | — | — | US | disclosed |
| EP-1114021-A1 | NEW SALTS OF HMG-CoA REDUCTASE INHIBITORS | Lek Pharmaceutical and Chemical Co. D.D. (SI) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000017150-A1 | NEW SALTS OF HMG-CoA REDUCTASE INHIBITORS | LEK PHARMACEUTICAL AND CHEMICAL COMPANY D.D. (DE) | 2000-03-30 | — | — | WO | disclosed |
| US-4999279-A | Polyamide, Unsaturated Monomer, Metal (Meth)acrylate, N-Nitrosoamine Compound; Printed Plates | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-03-12 | — | — | US | disclosed |
| EP-0324485-A2 | Photosensitive resin composition | Toyo Boseki Kabushiki Kaisha (JP) | 1989-07-19 | — | — | EP | disclosed |