Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 17/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4936772 | 1.00 | MTTP (0.54) | MTTPTDP1ALDH1A1MAOB | |
| SCHEMBL14102513 | 0.91 | ALDH1A1 (0.45) | MTTPALDH1A1 | |
| SCHEMBL4938636 | 0.88 | MTTP (0.51) | MTTPTDP1MAOB | |
| SCHEMBL4938642 | 0.88 | MTTP (0.51) | MTTPTDP1MAOB | |
| SCHEMBL14027828 | 0.87 | MTTP (0.54) | MTTPTDP1 | |
| SCHEMBL4938968 | 0.81 | MTTP (0.68) | MTTP | |
| SCHEMBL14027925 | 0.81 | MTTP (0.53) | MTTP | |
| SCHEMBL4938961 | 0.81 | MTTP (0.68) | MTTP | |
| SCHEMBL14027919 | 0.81 | MTTP (0.59) | MTTP | |
| SCHEMBL14027931 | 0.80 | MTTP (0.69) | MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249130-A1 | Gut microsomal triglyceride transport protein inhibitors | SIRTRIS PHARMACEUTICALS, INC. (US) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249130-A1 | Gut microsomal triglyceride transport protein inhibitors | MTTP, CETP, FABP2 | MTTP 1/4885TDP1 2015/4885ALDH1A1 983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.