SCHEMBL4936801

SCHEMBL4936801

CC1=C[C@@]2(C)C(CC[C@@H]3[C@H]2CC[C@]2(C)C(O)CC[C@@H]32)CC1=O

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.57
SHBG P04278 3/20 0.57
GPBAR1 Q8TDU6 3/20 0.57
AR P10275 2/20 0.57
SERPINA6 P08185 2/20 0.57
CYP3A4 P08684 2/20 0.57
HSD17B10 Q99714 2/20 0.57
NR3C1 P04150 1/20 0.57
PGR P06401 1/20 0.57
NR3C2 P08235 1/20 0.57
MGAM O43451 1/20 0.57
PRKCA P17252 1/20 0.51
LMNA P02545 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
TSHR P16473 1/20 0.50
CYP2C19 P33261 1/20 0.50
MBOAT4 Q96T53 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145680 1.00 CYP19A1 (0.57) CYP19A1SHBGGPBAR1ARSERPINA6
SCHEMBL11332329 1.00 CYP19A1 (0.57) CYP19A1SHBGGPBAR1ARSERPINA6
Acetic Acid SCHEMBL636808 0.95 CYP19A1 (0.53) CYP19A1SHBGGPBAR1ARSERPINA6
SCHEMBL10891187 0.87 CYP19A1 (0.56) CYP19A1SHBGGPBAR1ARSERPINA6
SCHEMBL10891182 0.87 CYP19A1 (0.56) CYP19A1SHBGGPBAR1ARSERPINA6
Acetic Acid Pentyl Ester SCHEMBL27748017 0.86 CYP19A1 (0.44) CYP19A1SHBGGPBAR1ARSERPINA6
SCHEMBL11324212 0.83 MBOAT4 (0.46) CYP19A1SHBGGPBAR1ARSERPINA6
SCHEMBL11324207 0.83 MBOAT4 (0.46) CYP19A1SHBGGPBAR1ARSERPINA6
SCHEMBL7082952 0.82 MBOAT4 (0.45) CYP19A1SHBGGPBAR1ARSERPINA6
SCHEMBL7082956 0.82 MBOAT4 (0.45) CYP19A1SHBGGPBAR1ARSERPINA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150152348-A1 SYSTEMS AND METHODS FOR COLLECTING, TRANSPORTING AND REPURPOSING OR DESTROYING UNUSED PHARMACEUTICALS SHARPS COMPLIANCE, INC. OF TEXAS 2015-06-04 US disclosed
US-20080207601-A1 Methods of and Compositions For the Prevention of Anxiety, Substance Abuse, and Dependence HYTHIAM , INC. (US) 2008-08-28 US disclosed
US-20080075772-A1 PHARMACEUTICAL COMPOSITIONS HAVING NOVEL SCORING PATTERNS AND METHODS OF USING THOSE COMPOSITIONS ACCU-BREAK TECHNOLOGIES, INC. 2008-03-27 US disclosed
US-4297350-A ORAL ANTIFERTILITY AGENTS; REVERSIBLE THE UPJOHN COMPANY (US) 1981-10-27 US disclosed