Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 20/20 | 1.00 |
| ▸ | F7 | P08709 | 20/20 | 1.00 |
| ▸ | F10 | P00742 | 19/20 | 1.00 |
| ▸ | KLKB1 | P03952 | 2/20 | 1.00 |
| ▸ | F2 | P00734 | 1/20 | 1.00 |
| ▸ | PLG | P00747 | 1/20 | 1.00 |
| ▸ | PLAU | P00749 | 1/20 | 1.00 |
| ▸ | PLAT | P00750 | 1/20 | 1.00 |
| ▸ | PROC | P04070 | 1/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 1/20 | 1.00 |
| ▸ | PRSS2 | P07478 | 1/20 | 1.00 |
| ▸ | PRSS3 | P35030 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3542727 | 1.00 | F11 (1.00) | F11F7F10KLKB1F2 | |
| SCHEMBL29373024 | 1.00 | F11 (1.00) | F11F7F10KLKB1F2 | |
| SCHEMBL5845798 | 0.92 | F11 (1.00) | F11F7F10KLKB1F2 | |
| SCHEMBL5844887 | 0.92 | F11 (0.91) | F11F7F10KLKB1F2 | |
| SCHEMBL3541978 | 0.91 | F11 (0.84) | F11F7F10KLKB1F2 | |
| SCHEMBL4736431 | 0.91 | F11 (0.87) | F11F7F10KLKB1F2 | |
| SCHEMBL5845779 | 0.91 | F11 (1.00) | F11F7F10KLKB1F2 | |
| SCHEMBL4737355 | 0.91 | F11 (0.86) | F11F7F10KLKB1F2 | |
| SCHEMBL3549704 | 0.91 | F11 (1.00) | F11F7F10KLKB1F2 | |
| SCHEMBL5846273 | 0.90 | F11 (0.87) | F11F7F10KLKB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180340163-A1 | RECOMBINANT SERINE PROTEASES | ACADEMISCH ZIEKENHUIS LEIDEN (NL) | 2018-11-29 | — | — | US | disclosed |
| US-20080026474-A1 | ASSAY FOR DIFFERENTIATING COMPOUNDS THAT MODULATE THE EXTRINSIC AND/OR INTRINSIC COAGULATION PATHWAYS | BRISTOL-MYERS SQUIBB COMPANY | 2008-01-31 | — | — | US | disclosed |