SCHEMBL49382

SCHEMBL49382

Nc1ccc(-c2ccc(N)c(Cl)c2)cc1Cl

nearest known ligand 0.94

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 8/20 0.94
TSHR P16473 8/20 0.94
ALDH1A1 P00352 6/20 0.94
MAPK1 P28482 1/20 0.94
ESR2 Q92731 1/20 0.74
TDP1 Q9NUW8 5/20 0.55
KMT2A Q03164 3/20 0.55
AHR P35869 3/20 0.55
MEN1 O00255 2/20 0.55
GAA P10253 2/20 0.53
ALOX15 P16050 3/20 0.48
HSD17B10 Q99714 3/20 0.48
THRB P10828 2/20 0.48
HPGD P15428 2/20 0.48
CASP1 P29466 1/20 0.48
RECQL P46063 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA4 P22748 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8872306 1.00 CYP3A4 (0.94) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL29365311 1.00 CYP3A4 (0.94) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL23137319 0.97 CYP3A4 (0.90) CYP3A4TSHRALDH1A1MAPK1ESR2
Hydrochloric Acid SCHEMBL2571374 0.97 CYP3A4 (1.00) CYP3A4TSHRALDH1A1MAPK1ESR2
Methane SCHEMBL27949876 0.97 CYP3A4 (0.90) CYP3A4TSHRALDH1A1MAPK1ESR2
Hydrochloric Acid SCHEMBL30242948 0.97 CYP3A4 (1.00) CYP3A4TSHRALDH1A1MAPK1ESR2
Hydrochloric Acid SCHEMBL29368557 0.97 CYP3A4 (1.00) CYP3A4TSHRALDH1A1MAPK1ESR2
Hydrochloric Acid SCHEMBL864592 0.97 CYP3A4 (1.00) CYP3A4TSHRALDH1A1MAPK1ESR2
Nitrogen SCHEMBL28358917 0.95 CYP3A4 (0.85) CYP3A4TSHRALDH1A1MAPK1ESR2
SCHEMBL29139595 0.92 CYP3A4 (0.81) CYP3A4TSHRALDH1A1MAPK1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4509 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4714998-A1 POLYAMIC ACID COMPOSITION WITH IMPROVED ADHESION AND POLYIMIDE CURED PRODUCT COMPRISING THE SAME PI Advanced Materials Co., Ltd. (KR) 2026-03-25 EP claimed
US-20260062517-A1 POLYAMIC ACID COMPOSITION WITH IMPROVED ADHESION AND POLYIMIDE CURED PRODUCT COMPRISING THE SAME PI ADVANCED MAT CO LTD (KR) 2026-03-05 US claimed
US-20260015454-A1 HIGH PERFORMANCE, AMBIENT CURE POLYURETHANES COMPRISING POLYCAPROLACTONE POLYOLS INGEVITY UK LTD (GB) 2026-01-15 US claimed
EP-4594381-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE Ingevity UK Ltd (GB) 2025-08-06 EP claimed
US-20250243313-A1 POLYCAPROLACTONE POLYOLS, ELASTOMERS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-31 US claimed
US-20250230274-A1 POLYCAPROLACTONE POLYOLS, POLYURETHANE DISPERSIONS, AND METHODS OF MAKING AND USING THE SAME INGEVITY UK LTD (GB) 2025-07-17 US claimed
EP-4565635-A1 BIO-BASED POLYOLS FOR HIGH PERFORMANCE POLYURETHANE APPLICATIONS Ingevity UK Ltd (GB) 2025-06-11 EP claimed
CN-119925257-A Photothermal conversion wood-based hydrogel and preparation method thereof 南京林业大学 2025-05-06 CN claimed
CN-114479450-B Homogeneous heterogeneous polyimide film and preparation method and application thereof 中国石油化工股份有限公司 2025-03-04 CN claimed
WO-2025039436-A1 IONIC LIQUID TYPE WATERBORNE POLYURETHANE DISPERSION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 广东腐蚀科学与技术创新研究院 2025-02-27 WO claimed
US-4172937-A REACTION OF A DIALDEHYDE AND DIAMINE IN A PHENOLIC COMPOUND ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1979-10-30 US claimed
US-4129558-A LITHIUM SALTS OF MONOHYDROXYALKYL-SUBSTITUTED CONJUGATED ALKADIENES PHILLIPS PETROLEUM COMPANY (US) 1978-12-12 US claimed
US-4111915-A LITHIUM ALKENOXIDES IN PREPARATION OF FUNCTIONAL LIQUID CONJUGATED DIENE POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1978-09-05 US claimed
US-4046745-A CONJUGATED DIENE POLYMERS WITH HYDROXY FUNCTIONALITY PHILLIPS PETROLEUM COMPANY (US) 1977-09-06 US claimed
US-4018742-A Imide-ring containing polyester and wire enamel containing same NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-04-19 US claimed
US-3991044-A Process for improving lightfastness of an azo pigment by heat treatment HERCULES INCORPORATED (US) 1976-11-09 US claimed
US-3979126-A Ball and process and composition of matter for production thereof ACUSHNET COMPANY (US) 1976-09-07 US claimed
US-3975330-A Imide-modified polyester resin and wire enamel containing the imide-modified polyester resin NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) 1976-08-17 US claimed
US-3943175-A Synthesis of pure 3,3'-diaminobenzidine CELANESE CORPORATION (US) 1976-03-09 US claimed
US-3941768-A One step diazotization coupling process CIBA-GEIGY AG (CH) 1976-03-02 US claimed