Tetrabuthylammonium

Tetrabuthylammonium

SCHEMBL4938830

CC(C)(C)c1ccc(B(c2ccc(C(C)(C)C)cc2)c2ccc(C(C)(C)C)cc2)cc1.CCCC[N+](CCCC)(CCCC)CCCC

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A1 O15245 3/20 0.43
HDAC3 O15379 2/20 0.39
HDAC1 Q13547 2/20 0.39
HDAC2 Q92769 2/20 0.39
SLC22A2 O15244 1/20 0.38
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
ALDH1A1 P00352 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TSHR P16473 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
HIF1A Q16665 1/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
LMNA P02545 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrabuthylammonium SCHEMBL7890102 0.84 SLC22A1 (0.44) SLC22A1HDAC3HDAC1HDAC2SLC22A2
Tetrabuthylammonium SCHEMBL28413492 0.80 LMNA (0.59) SLC22A1HDAC3HDAC1HDAC2HDAC8
Butylamine SCHEMBL1041720 0.80 HDAC3 (0.38) HDAC3HDAC1HDAC2HDAC8HDAC6
Tetrabuthylammonium SCHEMBL30595677 0.78 LMNA (0.40) SLC22A1HDAC3HDAC1HDAC2SLC22A2
SCHEMBL16491634 0.78 TSHR (0.52) SLC22A1HDAC1SLC22A2ALDH1A1TSHR
Tetrabuthylammonium SCHEMBL4940863 0.77 SLC22A1 (0.50) SLC22A1SLC22A2ALDH1A1SMN1; SMN2TSHR
Tetrabuthylammonium SCHEMBL106869 0.75 SRD5A2 (0.59) HDAC3HDAC1HDAC2HDAC8HDAC6
Tetrabuthylammonium SCHEMBL3062586 0.75 SLC22A1 (0.39) SLC22A1HDAC3HDAC1HDAC2SLC22A2
Tetrabuthylammonium SCHEMBL106868 0.73 HDAC1 (0.51) SLC22A1HDAC3HDAC1HDAC2HDAC8
Tetrabuthylammonium SCHEMBL29130221 0.73 LMNA (0.50) HDAC3HDAC1HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2620813-A1 LITHOGRAPHIC PRINTING PLATE ORIGINAL Eastman Kodak Company (US) 2013-07-31 EP disclosed
US-20080044765-A1 Ir Radical Polymerization-Type Photopolymer Plate Using Specific Binder Polymer KODAK POLYCHROME GRAPHICS JAPAN LTD (JP) 2008-02-21 US disclosed
EP-1757982-A1 NEGATIVE PHOTOSENSITIVE COMPOSITION AND NEGATIVE PHOTOSENSITIVE LITHOGRAPHY PLATE Kodak Polychrome Graphics Japan Ltd. (JP) 2007-02-28 EP disclosed