Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22121304 | 0.98 | MGMT (0.38) | MGMTCYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL31392289 | 0.82 | MGMT (0.39) | MGMTCYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL11002560 | 0.79 | TSHR (0.50) | ALDH1A1TDP1KMT2AHPGDLMNA | |
| SCHEMBL214271 | 0.79 | ALDH1A1 (0.45) | MGMTCYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL22394589 | 0.78 | HSP90AA1 (0.40) | CYP2C19ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL18894093 | 0.78 | ALDH1A1 (0.33) | MGMTCYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL16950621 | 0.77 | ALDH1A1 (0.41) | MGMTCYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL20560654 | 0.77 | ALDH1A1 (0.52) | MGMTCYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL962484 | 0.77 | MGMT (0.40) | MGMTCYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL29961217 | 0.77 | ALDH1A1 (0.41) | MGMTCYP1A2CYP2C19ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1705482-B1 | METHOD OF DETECTION, SEPARATION AND IDENTIFICATION FOR EXPRESSED TRACE PROTEIN/PEPTIDE | IMAI KAZUHIRO (JP) | 2017-09-27 | — | — | EP | disclosed |
| US-8796037-B2 | Method of detection, separation and identification for expressed trace protein/peptide | IMAI KAZUHIRO (JP) | 2014-08-05 | — | — | US | disclosed |
| US-20080280316-A1 | Mass spectrometry; liquid chromatography; automatic fractionation | IMAI KAZUHIRO | 2008-11-13 | — | — | US | disclosed |
| EP-1705482-A2 | METHOD OF DETECTION, SEPARATION AND IDENTIFICATION FOR EXPRESSED TRACE PROTEIN/PEPTIDE | Imai, Kazuhiro (JP) | 2006-09-27 | — | — | EP | disclosed |