Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | KDM1A | O60341 | 6/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 2/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20856475 | 0.83 | KDM1A (0.60) | MEN1KMT2AGAAKDM1APOLB | |
| SCHEMBL17154467 | 0.80 | KDM1A (0.58) | MEN1KMT2AGAAKDM1APOLB | |
| SCHEMBL23630584 | 0.80 | KDM1A (0.78) | MEN1KMT2AGAAKDM1APOLB | |
| SCHEMBL15673424 | 0.79 | KDM1A (0.66) | MEN1KMT2AGAAKDM1APOLB | |
| SCHEMBL9595420 | 0.79 | KDM1A (0.60) | MEN1KMT2AGAAKDM1APOLB | |
| SCHEMBL13530954 | 0.78 | KMT2A (0.55) | MEN1KMT2AGAAKDM1APOLB | |
| SCHEMBL9603057 | 0.75 | KDM1A (0.55) | MEN1KMT2AGAAKDM1APOLB | |
| SCHEMBL4939506 | 0.74 | KDM1A (0.75) | MEN1KMT2AGAAKDM1APOLB | |
| SCHEMBL902770 | 0.74 | KDM1A (1.00) | MEN1KMT2AKDM1APOLBL3MBTL1 | |
| SCHEMBL12019930 | 0.74 | KDM1A (0.58) | MEN1KMT2AGAAKDM1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | ACADEMIA SINICA (TW) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176889-A1 | 9-anilinoacridine alkylating agents | BCL9, MCL1, BCL9L | MEN1 1814/4885KMT2A 288/4885GAA 952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.