Styrene

Styrene

SCHEMBL4939721

C=C(C)C(=O)OCC1CC2CCC1O2.C=Cc1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 8/20 0.38
SLC6A4 P31645 6/20 0.38
PER2 O15055 1/20 0.37
CRY1 Q16526 1/20 0.37
CRY2 Q49AN0 1/20 0.37
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 2/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
KMT2A Q03164 2/20 0.34
LMNA P02545 1/20 0.34
GAA P10253 1/20 0.34
MAPK1 P28482 1/20 0.34
ADORA3 P0DMS8 1/20 0.32
HPGD P15428 1/20 0.32
XBP1 P17861 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PPM1B O75688 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL92234 0.85 ALDH1A1 (0.49) SLC6A3SLC6A4PER2CRY1CRY2
Styrene SCHEMBL10914482 0.77 ALDH1A1 (0.66) ALDH1A1
Styrene SCHEMBL35557 0.77 ALDH1A1 (0.66) ALDH1A1
Styrene SCHEMBL8536901 0.77 ALDH1A1 (0.66) ALDH1A1
SCHEMBL1469984 0.76 ALDH1A1 (0.50) SLC6A3SLC6A4ALDH1A1
Styrene SCHEMBL7558323 0.76 ALDH1A1 (0.64) ALDH1A1
Styrene SCHEMBL19970470 0.75 ALDH1A1 (0.62) ALDH1A1
Styrene SCHEMBL27741754 0.75 ALDH1A1 (0.62) ALDH1A1
Styrene SCHEMBL28389326 0.75 ALDH1A1 (0.62) ALDH1A1
Styrene SCHEMBL29253162 0.75 ALDH1A1 (0.62) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080227037-A1 Resist lower layer film composition and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-09-18 US disclosed