SCHEMBL4940443

SCHEMBL4940443

CCN(CC)CCNC(=O)NCCN(CC)CC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.59
ALDH1A1 P00352 5/20 0.50
LMNA P02545 2/20 0.50
SLC22A2 O15244 1/20 0.50
SLC22A1 O15245 1/20 0.50
TSHR P16473 1/20 0.50
ACHE P22303 1/20 0.50
MAPK1 P28482 1/20 0.50
CYP2C19 P33261 1/20 0.50
BLM P54132 2/20 0.49
PMP22 Q01453 1/20 0.49
KDM4E B2RXH2 1/20 0.47
HPGD P15428 1/20 0.47
NFKB1 P19838 1/20 0.46
KCNH2 Q12809 1/20 0.46
CYP3A4 P08684 2/20 0.45
POLB P06746 2/20 0.45
THRB P10828 1/20 0.45
ATM Q13315 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13853595 0.89 KMT2A (0.54) KMT2AALDH1A1LMNASLC22A2SLC22A1
SCHEMBL28922357 0.88 KMT2A (0.50) KMT2AALDH1A1LMNASLC22A2SLC22A1
SCHEMBL12912373 0.86 KMT2A (0.49) KMT2AALDH1A1LMNASLC22A2SLC22A1
SCHEMBL7260964 0.86 ALDH1A1 (0.59) KMT2AALDH1A1LMNAEPHX1
SCHEMBL13655355 0.85 ALDH1A1 (0.53) KMT2AALDH1A1LMNASLC22A2SLC22A1
SCHEMBL12891488 0.84 KMT2A (0.47) KMT2AALDH1A1LMNASLC22A2SLC22A1
SCHEMBL11292249 0.83 EPHX1 (0.55) KMT2AALDH1A1LMNASLC22A2SLC22A1
SCHEMBL14694183 0.83 ALDH1A1 (0.49) KMT2AALDH1A1LMNASLC22A2SLC22A1
SCHEMBL474091 0.83 ALDH1A1 (0.53) KMT2AALDH1A1LMNASLC22A2SLC22A1
SCHEMBL2835194 0.83 ALDH1A1 (0.49) KMT2AALDH1A1LMNASLC22A2SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1315849-B1 ZINC AND ZINC ALLOY ELECTROPLATING METHODS MACDERMID PLC (GB) 2008-06-04 EP claimed
EP-1315849-B1 ZINC AND ZINC ALLOY ELECTROPLATING METHODS MACDERMID PLC (GB) 2008-06-04 EP disclosed
US-7109375-B2 Zinc and zinc alloy electroplating additives and electroplating methods CITIBANK, N.A. 2006-09-19 US disclosed
US-20030192785-A1 Zinc and zinc alloy electroplating additives and electroplating methods CITIBANK, N.A. 2003-10-16 US disclosed
EP-1315849-A1 ZINC AND ZINC ALLOY ELECTROPLATING ADDITIVES AND ELECTROPLATING METHODS MacDermid Plc (GB) 2003-06-04 EP disclosed
WO-2002008497-A1 ZINC AND ZINC ALLOY ELECTROPLATING ADDITIVES AND ELECTROPLATING METHODS MACDERMID PLC (GB) 2002-01-31 WO disclosed