SCHEMBL4940573

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4941844	0.90	KDM4E (0.46)	HSP90AA1PDE2APDE10AKDM4EGAA
	SCHEMBL4936858	0.85	HSP90AA1 (0.60)	HSP90AA1KDM4EGAAMAPTL3MBTL1
	SCHEMBL3310440	0.78	HSP90AA1 (0.42)	HSP90AA1KDM4EGAASMN1; SMN2MEN1
	SCHEMBL4940445	0.77	HSP90AA1 (0.49)	HSP90AA1MAPTLMNA
	SCHEMBL4941855	0.77	PDE2A (0.42)	HSP90AA1PDE2APDE10AKDM4EGAA
	SCHEMBL930881	0.76	HSP90AA1 (0.50)	HSP90AA1PDE2APDE10AKDM4EGAA
	SCHEMBL4936564	0.76	ALDH1A1 (0.43)	HSP90AA1KDM4EMAPTL3MBTL1LMNA
	SCHEMBL4941329	0.75	HSP90AA1 (0.62)	HSP90AA1
	SCHEMBL1630519	0.73	HSP90AA1 (0.60)	HSP90AA1PIK3CDPIK3CBPDE10AKDM4E
	SCHEMBL3310378	0.73	KDM4E (0.43)	KDM4EMAPTL3MBTL1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.