Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3988495 | 0.83 | NOTUM (0.39) | NOTUMPKMLMNAPOLBALDH1A1 | |
| SCHEMBL3982881 | 0.82 | HPGD (0.40) | NOTUMPKMLMNAPOLBNPC1 | |
| SCHEMBL3988494 | 0.81 | POLB (0.40) | NOTUMPKMLMNAPOLBALDH1A1 | |
| SCHEMBL3979792 | 0.81 | NOTUM (0.39) | NOTUMPKMLMNAPOLBALDH1A1 | |
| SCHEMBL3982878 | 0.80 | POLB (0.39) | NOTUMPKMLMNAPOLBALDH1A1 | |
| SCHEMBL3984166 | 0.76 | HPGD (0.41) | MEN1KMT2ALMNATP53POLB | |
| SCHEMBL1096781 | 0.76 | USP30 (0.40) | NOTUMMEN1KMT2APKMLMNA | |
| SCHEMBL3989804 | 0.75 | HPGD (0.42) | LMNAPOLBNPC1RAB9A | |
| SCHEMBL1096337 | 0.75 | USP30 (0.39) | NOTUMPKMLMNAPOLBALDH1A1 | |
| SCHEMBL3989769 | 0.74 | LMNA (0.38) | LMNATP53POLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893572-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2008-03-05 | — | — | EP | claimed |
| WO-2006002099-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-01-05 | — | — | WO | claimed |