Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 2/20 | 0.59 |
| ▸ | CASP1 | P29466 | 3/20 | 0.57 |
| ▸ | CASP3 | P42574 | 2/20 | 0.57 |
| ▸ | CASP7 | P55210 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | BMP1 | P13497 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 3/20 | 0.54 |
| ▸ | MME | P08473 | 3/20 | 0.53 |
| ▸ | ECE1 | P42892 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | CASP4 | P49662 | 1/20 | 0.51 |
| ▸ | CASP5 | P51878 | 1/20 | 0.51 |
| ▸ | CASP9 | P55211 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3072927 | 0.94 | NMBR (0.63) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL27738734 | 0.94 | NMBR (0.63) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL10972700 | 0.93 | NMBR (0.61) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL10968279 | 0.92 | NMBR (0.68) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL3049265 | 0.91 | NMBR (0.57) | NMBRCASP1CASP3CASP7MAPT | |
| SCHEMBL3065558 | 0.91 | PLG (0.63) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL7436159 | 0.91 | NMBR (0.62) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL3036857 | 0.91 | NMBR (0.62) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL10899582 | 0.91 | NMBR (0.62) | NMBRMAPTGAAHTTLMNA | |
| SCHEMBL7627548 | 0.89 | NMBR (0.55) | NMBRCASP1CASP3CASP7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1253915-A1 | METHOD FOR TREATING STRESS WITH A PRECURSOR OF SEROTONIN | Massachusetts Institute of Technology (US) | 2002-11-06 | — | — | EP | claimed |
| WO-2001054681-A2 | COMPOSITION FOR TREATMENT OF STRESS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-08-02 | — | — | WO | claimed |
| EP-1910322-A2 | NOVEL BENZO [D][1,3]-DIOXOL DERIVATIVES | Concert Pharmaceuticals Inc. (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007016431-A2 | NOVEL BENZO [D] [1,3]-DIOXOL DERIVATIVES | CONCERT PHARMACEUTICALS INC. (US) | 2007-02-08 | — | — | WO | disclosed |
| US-4518587-A | NERVOUS SYSTEM DISORDERS | S.A. PANMEDICA (FR) | 1985-05-21 | — | — | US | disclosed |