Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | TERT | O14746 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 8/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL4941552 | 0.98 | APP (0.46) | APPTERTPSMB5APAF1KDM1A | |
| SCHEMBL4941135 | 0.98 | APP (0.48) | APPTERTPSMB5APAF1KDM1A | |
| Methylene Blue Cation SCHEMBL30367710 | 0.91 | APP (0.55) | APPTERTPSMB5APAF1KDM1A | |
| Methylene Blue Cation SCHEMBL1207285 | 0.91 | APP (0.55) | APPTERTPSMB5APAF1KDM1A | |
| Methylene Blue Cation SCHEMBL12312498 | 0.89 | APP (0.57) | APPTERTPSMB5APAF1KDM1A | |
| Methylene Blue Cation SCHEMBL29941578 | 0.89 | APP (0.57) | APPTERTPSMB5APAF1KDM1A | |
| Methylene Blue Cation SCHEMBL109755 | 0.89 | APP (0.57) | APPTERTPSMB5APAF1KDM1A | |
| Methylene Blue Cation SCHEMBL12312497 | 0.89 | APP (0.57) | APPTERTPSMB5APAF1KDM1A | |
| Methylene Blue Cation SCHEMBL12312491 | 0.89 | APP (0.57) | APPTERTPSMB5APAF1KDM1A | |
| Methylene Blue Cation SCHEMBL128584 | 0.89 | APP (0.57) | APPTERTPSMB5APAF1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7344823-B2 | Transient optical state change materials useful in copy-protected compact discs | VERIFICATION TECHNOLOGIES, INC. (US) | 2008-03-18 | — | — | US | disclosed |
| US-20080062838-A1 | MATERIALS FOR OPTICAL MEDIUM COPY-PROTECTION TRANSIENTLY REACTING TO A READER BEAM | VERIFICATION TECHNOLOGIES, INC. (US) | 2008-03-13 | — | — | US | disclosed |
| EP-1551817-A2 | TRANSIENT OPTICAL STATE CHANGE MATERIALS USEFUL IN COPY-PROTECTED COMPACT DISCS | Verification Technologies, Inc. (US) | 2005-07-13 | — | — | EP | disclosed |
| EP-1532623-A1 | MATERIALS FOR OPTICAL MEDIUM COPY-PROTECTION TRANSIENTLY REACTING TO A READER BEAM | Verification Technologies, Inc. (US) | 2005-05-25 | — | — | EP | disclosed |
| US-20040121262-A1 | Transient optical state change materials useful in copy-protected compact discs | SPENCER TRASK HEALTHCARE VENTURES LLC | 2004-06-24 | — | — | US | disclosed |
| WO-2004029672-A2 | TRANSIENT OPTICAL STATE CHANGE MATERIALS USEFUL IN COPY-PROTECTED COMPACT DISCS | VERIFICATION TECHNOLOGIES, INC. (US) | 2004-04-08 | — | — | WO | disclosed |
| US-20040004922-A1 | Materials for optical medium copy-protection transiently reacting to a reader beam | VERIFICATION TECHNOLOGIES, INC. | 2004-01-08 | — | — | US | disclosed |
| WO-2003107331-A1 | MATERIALS FOR OPTICAL MEDIUM COPY-PROTECTION TRANSIENTLY REACTING TO A READER BEAM | VERIFICATION TECHNOLOGIES, INC. (US) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040121262-A1 | Transient optical state change materials useful in copy-protected compact discs | RAD51, VCL, TRRAP | ACHE 2336/4885APP 1232/4885TERT 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.