Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4948642 | 0.92 | RARB (0.41) | CYP3A4CYP26A1MRGPRX4SMN1; SMN2 | |
| SCHEMBL4946321 | 0.89 | MAPT (0.40) | CYP3A4MAPTRAB9ALMNAL3MBTL1 | |
| SCHEMBL4944815 | 0.89 | MAPT (0.41) | CYP3A4MAPTRAB9ALMNAL3MBTL1 | |
| SCHEMBL4945312 | 0.89 | MRGPRX4 (0.43) | CYP3A4MAPTRAB9ALMNAL3MBTL1 | |
| SCHEMBL4946956 | 0.88 | MAPT (0.41) | CYP3A4MAPTRAB9ALMNAL3MBTL1 | |
| SCHEMBL4945300 | 0.88 | CYP3A4 (0.41) | CYP3A4MAPTRAB9ALMNAL3MBTL1 | |
| SCHEMBL4946310 | 0.88 | RAB9A (0.44) | CYP3A4MAPTRAB9ALMNAL3MBTL1 | |
| SCHEMBL4946301 | 0.88 | CYP3A4 (0.39) | CYP3A4MAPTRAB9ALMNAL3MBTL1 | |
| SCHEMBL5043943 | 0.87 | CYP3A4 (0.38) | CYP3A4MAPTRAB9ALMNAL3MBTL1 | |
| SCHEMBL4948201 | 0.87 | CYP3A4 (0.39) | CYP3A4MAPTRAB9ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513803-B1 | LIGANDS THAT ARE INHIBITORS OF THE RAR RECEPTORS | GALDERMA RES & DEV (FR) | 2008-06-18 | — | — | EP | disclosed |