SCHEMBL4943012

SCHEMBL4943012

C=C(C(=O)O)C(CC(F)(F)F)(CC(F)(F)F)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6053876 0.83 TET2 (0.38) TET2
SCHEMBL1118904 0.80 ACLY (0.33) TET2
SCHEMBL10662244 0.79 TET2 (0.32) TET2
SCHEMBL561209 0.76 TET2 (0.34) TET2
SCHEMBL10661684 0.74 KDM4E (0.33)
SCHEMBL5178000 0.73 TET2 (0.33) TET2
SCHEMBL5147447 0.73 TET2 (0.34) TET2
SCHEMBL4317323 0.73 TET2 (0.32) TET2
SCHEMBL676152 0.71 TET2 (0.37) TET2
SCHEMBL810647 0.70 TET2 (0.31) TET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
US-8553366-B1 Disk drive with actuator pivot bearing having a surface coating inhibiting lubricant migration WESTERN DIGITAL TECHNOLOGIES, INC. (US) 2013-10-08 US disclosed
US-20120277342-A1 METHACRYLATE-BASED BULKY SIDE-CHAIN SILOXANE CROSS LINKERS FOR OPTICAL MEDICAL DEVICES MCGEE JOSEPH A (US) 2012-11-01 US disclosed
US-7344731-B2 Rigid gas permeable lens material BAUSCH & LOMB INCORPORATED (US) 2008-03-18 US disclosed
US-20060276605-A1 Rigid gas permeable lens material BAUSCH & LOMB INCORPORATED 2006-12-07 US disclosed
EP-1303258-B1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2006-10-11 EP disclosed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US disclosed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP disclosed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO disclosed
US-4743667-A ACRYLATED SILOXXANES, OXYGEN PERMEABLE NIPPON CONTACT LENS, INC. (JP) 1988-05-10 US disclosed
US-4602074-A SILICON CONTAINING ACRYLIC MONOMER NIPPON CONTACT LENS MANUFACTURING LTD. (JP) 1986-07-22 US disclosed