SCHEMBL49434

SCHEMBL49434

[c]1ccc(Oc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 7/20 0.67
TSHR P16473 1/20 0.67
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50
MAOA P21397 1/20 0.50
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
MAOB P27338 1/20 0.44
GSTP1 P09211 1/20 0.41
SOS1 Q07889 1/20 0.41
CA9 Q16790 1/20 0.41
PARP10 Q53GL7 1/20 0.41
PLA2G2A P14555 1/20 0.41
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40
NLRP3 Q96P20 1/20 0.40
SRD5A2 P31213 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28744175 1.00 LTA4H (0.67) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL27870037 0.97 LTA4H (0.63) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL27736985 0.97 LTA4H (0.63) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL27737034 0.97 LTA4H (0.63) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL8535186 0.97 LTA4H (0.63) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL27824058 0.97 LTA4H (0.63) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL27917515 0.97 LTA4H (0.63) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL28807910 0.97 LTA4H (0.63) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL27832320 0.97 LTA4H (0.63) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL28088126 0.91 LTA4H (0.55) LTA4HTSHRNR1H2BAXMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16596 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344265-A Amide compound and preparation method and application thereof 河北大学 2024-07-16 CN claimed
US-20240197888-A1 SOS1 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS BIOTHERYX, INC. 2024-06-20 US claimed
US-20240190885-A1 KRAS PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS BIOTHERYX INC (US) 2024-06-13 US claimed
CN-118108698-A Beta-carbonyl sulfinolactone compound and preparation method thereof 华中师范大学 2024-05-31 CN claimed
WO-2024096482-A1 ADHESIVE COMPOSITION, ADHESIVE SHEET MANUFACTURED THEREFROM, AND IMAGE DISPLAY DEVICE 동우화인켐 주식회사 2024-05-10 WO claimed
WO-2024086161-A2 EPHA2 TARGETING AGENTS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-04-25 WO claimed
US-20240132531-A1 NOVEL GALACTOSIDE INHIBITOR OF GALECTINS GALECTO BIOTECH AB (DK) 2024-04-25 US claimed
CN-117903107-A [ (1-Sulfone-2-sulfinate) ethyl ] arene compound and preparation method thereof 华中师范大学 2024-04-19 CN claimed
EP-3778576-B1 2-CYANOPYRIMIDIN-4-YL CARBAMATE OR UREA DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME HANLIM PHARMACEUTICAL CO LTD (KR) 2024-04-17 EP claimed
US-11958871-B2 Inhibitors of bacterial glutaminyl cyclases for use in the treatment of periodontal and related diseases Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2024-04-16 US claimed
US-4093712-A ANTITHROMBOGENIC AGENTS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) 1978-06-06 US claimed
US-4066773-A ANTITHROMBOSIS MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1978-01-03 US claimed
US-4064265-A ANTHELMINTICS CIBA-GEIGY CORPORATION (US) 1977-12-20 US claimed
US-4048153-A Azo dyes having an optionally substituted 1-azo-3-nitro-4-arylaminophenyl nucleus SANDOZ LTD. (CH) 1977-09-13 US claimed
US-4039539-A 1,2,4-Triazole-azo-aniline cationic dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-08-02 US claimed
US-4022962-A DENTAL PLAQUE INHIBITORS COOPER LABORATORIES, INC. (US) 1977-05-10 US claimed
US-3994724-A SUBSTITUTED ANILINE PHOTOCONDUCTOR SCOTT PAPER COMPANY (US) 1976-11-30 US claimed
US-3995054-A MITICIDES ZOECON CORPORATION (US) 1976-11-30 US claimed
US-3989695-A 7β-Amino-cepham-3-ol-4-carboxylic acid compounds CIBA-GEIGY CORPORATION (US) 1976-11-02 US claimed
US-3959332-A N-(2-NITRO-4-ARYLOXYSULFONYL-PHENYL)-ARYLENEDIAMINES, DYES SANDOZ LTD. (CH) 1976-05-25 US claimed