Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | GNRHR | P30968 | 1/20 | 0.34 |
| ▸ | EIF4E | P06730 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4262046 | 0.84 | POLB (0.46) | MAPTALDH1A1SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL4260398 | 0.83 | NR3C2 (0.56) | MAPTALDH1A1SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL4264485 | 0.82 | NR3C2 (0.49) | MAPTALDH1A1SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL4258380 | 0.81 | POLB (0.51) | MAPTALDH1A1SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL4261043 | 0.80 | POLB (0.49) | MAPTALDH1A1SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL4266185 | 0.79 | RAB9A (0.50) | MAPTALDH1A1SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL4266653 | 0.78 | POLB (0.48) | MAPTALDH1A1SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL4263181 | 0.78 | NR3C2 (0.55) | MAPTALDH1A1SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL4261993 | 0.77 | NR3C2 (0.46) | MAPTALDH1A1SMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL4258381 | 0.76 | NR3C2 (0.47) | MAPTALDH1A1SMN1; SMN2KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008508314-A | — | — | 2008-03-21 | — | — | JP | claimed |
| EP-1778242-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS | IRM LLC (BM) | 2007-05-02 | — | — | EP | claimed |
| WO-2006015259-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS | IRM LLC (BM) | 2006-02-09 | — | — | WO | claimed |