Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702595 | 0.90 | ESR1 (0.47) | ESR1ESR2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4755511 | 0.80 | HRH1 (0.50) | CYP1A2CYP3A4CYP2C19ALDH1A1MEN1 | |
| SCHEMBL1595841 | 0.79 | ESR1 (0.50) | ESR1ESR2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27973293 | 0.79 | CYP19A1 (0.41) | ALDH1A1CNR1CNR2LMNASLC6A3 | |
| SCHEMBL4607511 | 0.78 | ESR1 (0.58) | ESR1ESR2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1596654 | 0.75 | ESR1 (0.46) | ESR1ESR2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9838263 | 0.75 | ESR1 (0.46) | ESR1ESR2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9623581 | 0.73 | ESR1 (0.44) | ESR1ESR2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9623721 | 0.73 | ESR1 (0.44) | ESR1ESR2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4661057 | 0.73 | ESR1 (0.44) | ESR1ESR2CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207822-A1 | COMPOSITION AND ASSOCIATED METHOD | GENERAL ELECTRIC COMPANY (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080203012-A1 | MEMBRANE, APPARATUS, AND ASSOCIATED METHOD | GENERAL ELECTRIC COMPANY (US) | 2008-08-28 | — | — | US | disclosed |