SCHEMBL27973293

SCHEMBL27973293

Cc1ccc(C(CCC#N)c2ccc(C)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.41
CNR1 P21554 1/20 0.39
CNR2 P34972 1/20 0.39
ALDH1A1 P00352 4/20 0.38
CYP2A6 P11509 1/20 0.38
TSHR P16473 1/20 0.37
CHRNA7 P36544 1/20 0.35
ALOX5 P09917 1/20 0.35
CASR P41180 1/20 0.35
GLA P06280 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
GAA P10253 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
FFAR1 O14842 1/20 0.33
LMNA P02545 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4755511 0.80 HRH1 (0.50) CYP19A1ALDH1A1TSHRCASRSMN1; SMN2
SCHEMBL4944014 0.79 ESR1 (0.48) CYP19A1CNR1CNR2ALDH1A1TSHR
SCHEMBL15787636 0.79 ALDH1A1 (0.36) ALDH1A1CYP2A6TSHRCHRNA7ALOX5
SCHEMBL13930328 0.78 ALDH1A1 (0.41) CYP19A1CNR1CNR2ALDH1A1CYP2A6
P-Xylene SCHEMBL28290544 0.75 ALDH1A1 (0.46) ALDH1A1CYP2A6TSHRGLASMN1; SMN2
SCHEMBL29723649 0.73 CNR1 (0.56) CYP19A1CNR1CNR2ALDH1A1TSHR
SCHEMBL9330269 0.73 CYP19A1 (0.46) CYP19A1CNR1CNR2CHRNA7CASR
SCHEMBL12381752 0.72 CHRNA7 (0.32) CHRNA7
SCHEMBL8764025 0.71 ESR1 (0.50) ALDH1A1CYP2A6CHRNA7ALOX5GLA
SCHEMBL15656198 0.71 CYP19A1 (0.44) CYP19A1CNR1CNR2TSHRCHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104030870-A Method for preparing beta-cyan ketone UNIV NORTHWEST NORMAL 2014-09-10 CN disclosed