SCHEMBL4944757

SCHEMBL4944757

C=CC[C@@]1(n2cnc3c(N)ncnc32)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 5/20 0.53
ADORA2A P29274 4/20 0.53
GMPS P49915 1/20 0.53
SLC28A1 O00337 2/20 0.48
PI4KA P42356 2/20 0.48
PI4K2B Q8TCG2 2/20 0.48
PI4K2A Q9BTU6 2/20 0.48
PI4KB Q9UBF8 2/20 0.48
DPP4 P27487 1/20 0.48
MEN1 O00255 1/20 0.48
MAP3K7 O43318 1/20 0.48
SLC28A2 O43868 1/20 0.48
GAPDH P04406 1/20 0.48
MAPK1 P28482 1/20 0.48
ADORA2B P29275 1/20 0.48
ADORA1 P30542 1/20 0.48
STAT6 P42226 1/20 0.48
KMT2A Q03164 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
DOT1L Q8TEK3 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29508945 1.00 ADORA3 (0.53) ADORA3ADORA2AGMPSSLC28A1PI4KA
Tetrazole SCHEMBL27523959 0.91 ADORA3 (0.46) ADORA3ADORA2AGMPSSLC28A1PI4KA
SCHEMBL8003530 0.89 ADORA3 (0.53) ADORA3ADORA2AGMPSSLC28A1PI4KA
SCHEMBL30676636 0.88 ADORA3 (0.53) ADORA3ADORA2AGMPSSLC28A1PI4KA
SCHEMBL5181220 0.88 ADORA3 (0.53) ADORA3ADORA2AGMPSSLC28A1PI4KA
SCHEMBL277610 0.88 ADORA3 (0.53) ADORA3ADORA2AGMPSSLC28A1PI4KA
SCHEMBL35210134 0.88 ADORA3 (0.53) ADORA3ADORA2AGMPSSLC28A1PI4KA
Psicofuranine SCHEMBL29441281 0.88 GMPS (0.61) ADORA3ADORA2AGMPSSLC28A1PI4KA
Psicofuranine SCHEMBL691065 0.88 GMPS (0.61) ADORA3ADORA2AGMPSSLC28A1PI4KA
Psicofuranine SCHEMBL9389898 0.88 GMPS (0.61) ADORA3ADORA2AGMPSSLC28A1PI4KA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112301118-B Method and kit for simultaneously obtaining RNA abundance and active RNA polymerase sites in full transcriptome range 浙江大学 2022-05-13 CN claimed
CN-111154837-B Method for detecting RNA N6-methyladenine modification in single base resolution in full transcriptome range 浙江大学 2021-05-18 CN claimed
CN-112301118-A Method and kit for simultaneously obtaining RNA abundance and active RNA polymerase sites in full transcriptome range 浙江大学 2021-02-02 CN claimed
CN-111154837-A Method and kit for detecting RNA N6-methyladenine modification in single base resolution in full transcriptome range 浙江大学 2020-05-15 CN claimed
US-11859248-B2 Nucleic acid modification and identification method IMBA—INSTITUT FÜR MOLEKULARE BIOTECHNOLOGIE GMBH (AT) 2024-01-02 US disclosed
CN-110520540-B Nucleic acid modification and identification method IMBA-莫利库尔生物技术研究所 2023-10-03 CN disclosed
CN-116685684-A Compositions and methods for treating type 1a glycogen storage disease 比姆医疗股份有限公司 2023-09-01 CN disclosed
WO-2023114963-A1 COMPOSITIONS AND METHODS FOR SELECTIVELY LABELING SECONDARY AMINES EMORY UNIVERSITY (US) 2023-06-22 WO disclosed
US-20230054714-A1 NUCLEIC ACID MODIFICATION AND IDENTIFICATION METHOD IMBA INST MOLEKULARE BIOTECH (AT) 2023-02-23 US disclosed
CN-115279398-A Compositions and methods for treating liquid cancers 比姆医疗股份有限公司 2022-11-01 CN disclosed
CN-114787385-A Methods and systems for detecting nucleic acid modifications 芝加哥大学 2022-07-22 CN disclosed
CN-114641567-A Compositions and methods for editing mutations to allow transcription or expression 比姆医疗股份有限公司 2022-06-17 CN disclosed
CN-109952297-A Compound 奥斯陆大学 2019-06-28 CN disclosed
US-20190177785-A1 NUCLEIC ACID MODIFICATION AND IDENTIFICATION METHOD IMBA - INSTITUT FÜR MOLEKULARE BIOTECHNOLOGIE GMBH (AT) 2019-06-13 US disclosed
WO-2018189367-A1 NUCLEIC ACID MODIFICATION AND IDENTIFICATION METHOD IMBA - INSTITUT FÜR MOLEKULARE BIOTECHNOLOGIE GMBH (AT) 2018-10-18 WO disclosed
US-20080168707-A1 Additive for hydrocarbon fuel and related processes consisting of compounds of adenosine phosphates ENVIROFUELS LLC (US) 2008-07-17 US disclosed
WO-2007136548-A2 ADDITIVE FOR HYDROCARBON FUEL AND RELATED PROCESSES CONSISTING OF COMPOUNDS OF ADENOSINE PHOSPHATES ENVIROFUELS, LLC (US) 2007-11-29 WO disclosed
CN-1032815-C Selective adenosine receptor agents MERRELL DOW PHARMA (US) 1996-09-18 CN disclosed
CN-1055181-A SELECTIVE ADENOSINE RECEPTOR AGENTS MERRELL DOW PHARMA (US) 1991-10-09 CN disclosed
US-4992535-A Cardiovascular disorders; side effect reduction G. D. SEARLE & CO. (US) 1991-02-12 US disclosed