SCHEMBL4944972

SCHEMBL4944972

O=c1[nH]c(=O)n(CCC[SiH3])c(=O)[nH]1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33
ATM Q13315 1/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
LMNA P02545 2/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
APEX1 P27695 1/20 0.32
KDM4E B2RXH2 3/20 0.31
GAA P10253 2/20 0.31
PDE4A P27815 2/20 0.30
ADORA2A P29274 2/20 0.30
PDE4B Q07343 2/20 0.30
PDE4C Q08493 2/20 0.30
PDE4D Q08499 2/20 0.30
ADORA3 P0DMS8 1/20 0.30
ADORA2B P29275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2026591 0.83 TYMP (0.38) MAPTATMALDH1A1HPGDLMNA
SCHEMBL9230353 0.77 ALDH1A1 (0.50) MAPTATMALDH1A1HPGDTSHR
SCHEMBL2808249 0.77 MAPT (0.33) MAPTATMALDH1A1HPGDLMNA
SCHEMBL29076841 0.77 MAPT (0.37) MAPTATMALDH1A1HPGDLMNA
SCHEMBL2784423 0.77 ATM (0.53) MAPTATMALDH1A1LMNATSHR
SCHEMBL11709001 0.76 ATM (0.51) MAPTATMALDH1A1LMNATSHR
SCHEMBL1727945 0.76 ALDH1A1 (0.45) ALDH1A1HPGDLMNAHTTSMN1; SMN2
SCHEMBL2048833 0.76 MAPT (0.47) MAPTATMALDH1A1HPGDLMNA
SCHEMBL678855 0.74 HTT (0.49) MAPTATMALDH1A1HPGDLMNA
SCHEMBL4954143 0.74 HTT (0.49) MAPTATMALDH1A1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023157943-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM FORMING COMPOSITION HAVING UNSATURATED BOND AND CYCLIC STRUCTURE 日産化学株式会社 2023-08-24 WO disclosed
EP-1530576-B1 HETEROCYCLIC HALAMINE-SUBSTITUTED SILOXANES FOR USE IN BIOCIDAL COATINGS AND MATERIALS UNIV AUBURN (US) 2008-02-13 EP disclosed
US-20080003438-A1 Heterocyclic siloxanes for use in biocidal coatings and materials AUBURN UNIVERSITY (US) 2008-01-03 US disclosed
US-6969769-B2 N-halamine siloxanes for use in biocidal coatings and materials VANSON HALOSOURCE, INC. (US) 2005-11-29 US disclosed
EP-1530576-A2 HETEROCYCLIC HALAMINE-SUBSTITUTED SILOXANES FOR USE IN BIOCIDAL COATINGS AND MATERIALS Auburn University (US) 2005-05-18 EP disclosed
US-20040127667-A1 N-halamine siloxanes for use in biocidal coatings and materials AUBURN UNIVERSITY 2004-07-01 US disclosed
WO-2003106466-A2 N-HALAMINE SILOXANES FOR USE IN BIOCIDAL COATINGS AND MATERIALS AUBURN UNIVERSITY (US) 2003-12-24 WO disclosed